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MetaCyc Reaction: 3.5.1.23

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.5.1.23

Enzymes and Genes:

Saccharomyces cerevisiae : phytoceramidase Inferred from experiment : YPC1

In Pathway: sphingolipid recycling and degradation (yeast)

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: ceramidase

Enzyme Commission Synonyms: acylsphingosine deacylase, glycosphingolipid ceramide deacylase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 389.21545 Inferred by computational analysis [Latendresse13]

Citations: [Nilsson69, Yavin69]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:3.5.1.23 , ENZYME:EC:3.5.1.23 , IUBMB-ExplorEnz:EC:3.5.1.23


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Nilsson69: Nilsson A (1969). "The presence of spingomyelin- and ceramide-cleaving enzymes in the small intestinal tract." Biochim Biophys Acta 176(2);339-47. PMID: 5775951

Yavin69: Yavin E, Gatt S (1969). "Enzymatic hydrolysis of sphingolipids. 8. Further purification and properties of rat brain ceramidase." Biochemistry 8(4);1692-8. PMID: 5805303


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sat May 23, 2015, BIOCYC14B.