|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions → Protein-Modification Reactions|
|Reactions Classified By Substrate → Macromolecule Reactions → Protein-Reactions → Protein-Modification Reactions|
EC Number: 18.104.22.168
Enzymes and Genes:
|Escherichia coli K-12 substr. MG1655 :||chemotaxis protein methyltransferase
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Mass balance status: Balanced.
Enzyme Commission Primary Name: protein-glutamate O-methyltransferase
Enzyme Commission Synonyms: methyl-accepting chemotaxis protein O-methyltransferase, S-adenosylmethionine-glutamyl methyltransferase, methyl-accepting chemotaxis protein methyltransferase II, S-adenosylmethionine:protein-carboxyl O-methyltransferase, protein methylase II, MCP methyltransferase I, MCP methyltransferase II, protein O-methyltransferase, protein(aspartate)methyltransferase, protein(carboxyl)methyltransferase, protein carboxyl-methylase, protein carboxyl-O-methyltransferase, protein carboxylmethyltransferase II, protein carboxymethylase, protein carboxymethyltransferase, protein methyltransferase II
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -35.519257 [Latendresse13]
Enzyme Commission Summary:
Forms ester groups with L-glutamate residues in a number of membrane proteins.
Unification Links: KEGG:R02623
BurgessCassler82: Burgess-Cassler A, Ullah AH, Ordal GW (1982). "Purification and characterization of Bacillus subtilis methyl-accepting chemotaxis protein methyltransferase II." J Biol Chem 257(14);8412-7. PMID: 6806296
Simms87: Simms SA, Stock AM, Stock JB (1987). "Purification and characterization of the S-adenosylmethionine:glutamyl methyltransferase that modifies membrane chemoreceptor proteins in bacteria." J Biol Chem 262(18);8537-43. PMID: 3298235
Springer77: Springer WR, Koshland DE (1977). "Identification of a protein methyltransferase as the cheR gene product in the bacterial sensing system." Proc Natl Acad Sci U S A 74(2);533-7. PMID: 322131
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