|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions → Composite Reactions → Electron-Transfer-Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
Enzymes and Genes:
|Escherichia coli K-12 substr. MG1655 :||dimethyl sulfoxide reductase
Reaction Locations: inner membrane (sensu Gram-negative Bacteria)
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: dimethylsulfoxide reductase
Enzyme Commission Synonyms: DMSO reductase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -25.12525 [Latendresse13]
Enzyme Commission Summary:
Contains molybdopterin and [4Fe-4S] clusters. Also reduces pyridine N-oxide and trimethylamine N-oxide, with lower activity, to the corresponding amines.
Rothery99: Rothery RA, Trieber CA, Weiner JH (1999). "Interactions between the molybdenum cofactor and iron-sulfur clusters of Escherichia coli dimethylsulfoxide reductase." J Biol Chem 274(19);13002-9. PMID: 10224050
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