|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions → Composite Reactions → Electron-Transfer-Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 126.96.36.199
Enzymes and Genes:
|Escherichia coli K-12 substr. MG1655:||dimethyl sulfoxide reductase: dmsA, dmsB, dmsC|
Reaction Locations: inner membrane (sensu Gram-negative Bacteria)
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: dimethylsulfoxide reductase
Enzyme Commission Synonyms: DMSO reductase
Standard Gibbs Free Energy (ΔrG'°): -25.12525 kcal/mol [Latendresse13]
Enzyme Commission Summary:
Contains molybdopterin and [4Fe-4S] clusters. Also reduces pyridine N-oxide and trimethylamine N-oxide, with lower activity, to the corresponding amines.
Rothery99a: Rothery RA, Trieber CA, Weiner JH (1999). "Interactions between the molybdenum cofactor and iron-sulfur clusters of Escherichia coli dimethylsulfoxide reductase." J Biol Chem 274(19);13002-9. PMID: 10224050
©2016 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493