Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 1.1.1.216

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 1.1.1.216

Enzymes and Genes:
NADP+-dependent farnesol dehydrogenase 1 Inferred from experiment : SDR-1 ( Aedes aegypti )
farnesol dehydrogenase Inferred from experiment ( Ipomoea batatas )
aldehyde reductase, NADPH-dependent : yahK ( Escherichia coli K-12 substr. MG1655 )
NADP+-dependent aldehyde reductase : ybbO ( Escherichia coli K-12 substr. MG1655 )
aldehyde reductase, NADPH-dependent : ahr ( Escherichia coli K-12 substr. MG1655 )
NADPH-dependent aldehyde reductase : yqhD ( Escherichia coli K-12 substr. MG1655 )

In Pathway: farnesylcysteine salvage pathway , juvenile hormone III biosynthesis I , juvenile hormone III biosynthesis II

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: farnesol dehydrogenase (NADP+)

Enzyme Commission Synonyms: NADP+-farnesol dehydrogenase, farnesol (nicotinamide adenine dinucleotide phosphate) dehydrogenase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -0.25646973 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Also acts, more slowly, on (2Z,6E)-farnesol, geraniol, citronerol and nerol.

Gene-Reaction Schematic: ?

Instance reaction of [an alcohol + NADP+ = an aldehyde + NADPH + H+] (1.1.1.2):
i1: (2E,6E)-farnesol + NADP+ ↔ (2E,6E)-farnesal + NADPH + H+ (1.1.1.216)

Unification Links: KEGG:R03264 , Rhea:14700

Relationship Links: BRENDA:EC:1.1.1.216 , ENZYME:EC:1.1.1.216 , IUBMB-ExplorEnz:EC:1.1.1.216


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sun Nov 23, 2014, BIOCYC13B.