Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 2.3.1.4

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.3.1.4

Enzymes and Genes:
glucosamine-6-phosphate acetyltransferase Inferred from experiment Inferred by computational analysis : GNA1 ( Arabidopsis thaliana col )
glucosamine-6-phosphate N-acetyltransferase Inferred from experiment : Gna ( Aedes aegypti )
glucosamine 6-phosphate N-acetylase Inferred from experiment : GNA ( Giardia intestinalis )
glucosamine-6-phosphate N-acetyltransferase 1 Inferred from experiment : Gnpnat1 ( Mus musculus )
glucosamine-6-phosphate N-acetyltransferase 1 Inferred from experiment : GNA1 ( Saccharomyces cerevisiae )

In Pathway: UDP-N-acetyl-D-glucosamine biosynthesis II , UDP-N-acetyl-D-galactosamine biosynthesis II

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: glucosamine-phosphate N-acetyltransferase

Enzyme Commission Synonyms: phosphoglucosamine transacetylase, phosphoglucosamine acetylase, glucosamine-6-phosphate acetylase, D-glucosamine-6-P N-acetyltransferase, aminodeoxyglucosephosphate acetyltransferase, glucosamine 6-phosphate acetylase, glucosamine 6-phosphate N-acetyltransferase, N-acetylglucosamine-6-phosphate synthase, phosphoglucosamine N-acetylase, glucosamine-6-phosphate N-acetyltransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -6.538269 Inferred by computational analysis [Latendresse13]

Citations: [Boehmelt00, PATTABIRAMAN62, DAVIDSON57]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R02058 , Rhea:10292

Relationship Links: BRENDA:EC:2.3.1.4 , ENZYME:EC:2.3.1.4 , IUBMB-ExplorEnz:EC:2.3.1.4 , UniProt:RELATED-TO:O13738 , UniProt:RELATED-TO:P43577


References

Boehmelt00: Boehmelt G, Fialka I, Brothers G, McGinley MD, Patterson SD, Mo R, Hui CC, Chung S, Huber LA, Mak TW, Iscove NN (2000). "Cloning and characterization of the murine glucosamine-6-phosphate acetyltransferase EMeg32. Differential expression and intracellular membrane association." J Biol Chem 275(17);12821-32. PMID: 10777580

DAVIDSON57: DAVIDSON EA, BLUMENTHAL HJ, ROSEMAN S (1957). "Glucosamine metabolism. II. Studies on glucosamine 6-phosphate N-acetylase." J Biol Chem 226(1);125-33. PMID: 13428743

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

PATTABIRAMAN62: PATTABIRAMAN TN, BACHHAWAT BK (1962). "Purification of glucosamine-6-phosphate N-acetylase from sheep brain." Biochim Biophys Acta 59;681-9. PMID: 14484387


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Thu Dec 18, 2014, BIOCYC14B.