MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:

Aedes aegypti: glucosamine-6-phosphate N-acetyltransferaseInferred from experiment: Gna
Arabidopsis thaliana col: glucosamine-6-phosphate acetyltransferaseInferred from experimentInferred by computational analysis: GNA1
Giardia intestinalis: glucosamine 6-phosphate N-acetylaseInferred from experiment: GNA
Mus musculus: glucosamine-6-phosphate N-acetyltransferase 1Inferred from experiment: Gnpnat1
Saccharomyces cerevisiae: glucosamine-6-phosphate N-acetyltransferase 1Inferred from experiment: GNA1

In Pathway: UDP-N-acetyl-D-glucosamine biosynthesis II, UDP-N-acetyl-D-galactosamine biosynthesis II

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: glucosamine-phosphate N-acetyltransferase

Enzyme Commission Synonyms: phosphoglucosamine transacetylase, phosphoglucosamine acetylase, glucosamine-6-phosphate acetylase, D-glucosamine-6-P N-acetyltransferase, aminodeoxyglucosephosphate acetyltransferase, glucosamine 6-phosphate acetylase, glucosamine 6-phosphate N-acetyltransferase, N-acetylglucosamine-6-phosphate synthase, phosphoglucosamine N-acetylase, glucosamine-6-phosphate N-acetyltransferase

Standard Gibbs Free Energy (ΔrG): -6.538269 kcal/molInferred by computational analysis [Latendresse13]

Citations: [Boehmelt00, Pattabiraman62, Davidson57]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R02058, Rhea:10292

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:, UniProt:RELATED-TO:O13738, UniProt:RELATED-TO:P43577


Boehmelt00: Boehmelt G, Fialka I, Brothers G, McGinley MD, Patterson SD, Mo R, Hui CC, Chung S, Huber LA, Mak TW, Iscove NN (2000). "Cloning and characterization of the murine glucosamine-6-phosphate acetyltransferase EMeg32. Differential expression and intracellular membrane association." J Biol Chem 275(17);12821-32. PMID: 10777580

Davidson57: Davidson EA, Blumenthal HJ, Roseman S (1957). "Glucosamine metabolism. II. Studies on glucosamine 6-phosphate N-acetylase." J Biol Chem 226(1);125-33. PMID: 13428743

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Pattabiraman62: Pattabiraman TN, Bachhawat BK (1962). "Purification of glucosamine-6-phosphate N-acetylase from sheep brain." Biochim Biophys Acta 59;681-9. PMID: 14484387

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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