MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: glycine N-acyltransferase

Enzyme Commission Synonyms: glycine acyltransferase, glycine-N-acylase

Taxonomic Range: Metazoa

Standard Gibbs Free Energy (ΔrG in kcal/mol): 290.23016Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
The CoA derivatives of a number of aliphatic and aromatic acids, but not phenylacetyl-CoA or (indol-3-yl)acetyl-CoA, can act as donor. Not identical with EC glutamine N-acyltransferase or EC glycine N-benzoyltransferase.

Citations: [Webster76, Schachter54, Nandi79]

Unification Links: KEGG:R00395, Rhea:19872

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Nandi79: Nandi DL, Lucas SV, Webster LT (1979). "Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization." J Biol Chem 254(15);7230-7. PMID: 457678

Schachter54: Schachter D, Taggart JV (1954). "Glycine N-acylase: purification and properties." J Biol Chem 208(1);263-75. PMID: 13174534

Webster76: Webster LT, Siddiqui UA, Lucas SV, Strong JM, Mieyal JJ (1976). "Identification of separate acyl- CoA:glycine and acyl-CoA:L-glutamine N-acyltransferase activities in mitochondrial fractions from liver of rhesus monkey and man." J Biol Chem 251(11);3352-8. PMID: 931988

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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