MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:

Arabidopsis thaliana col : glycolate dehydrogenase / D-lactate dehydrogenase Inferred from experiment : AT5G06580
Escherichia coli K-12 substr. MG1655 : glycolate oxidase Inferred from experiment : glcD , glcE , glcF
Paracoccus denitrificans NCIMB 8944 : glycolate oxidase Inferred from experiment

In Pathway: glycolate and glyoxylate degradation II , glycolate and glyoxylate degradation I , glycolate and glyoxylate degradation III

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: glycolate dehydrogenase

Enzyme Commission Synonyms: glycolate oxidoreductase, glycolic acid dehydrogenase, glycolate:(acceptor) 2-oxidoreductase

Enzyme Commission Summary:
Also acts on (R)-lactate. 2,6-Dichloroindophenol and phenazine methosulfate can act as acceptors.

Citations: [Lord72]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Instance reaction of [(R)-lactate + 2 an oxidized c-type cytochrome → pyruvate + 2 a reduced c-type cytochrome + 2 H+] (
i1: (R)-lactate + 2 an oxidized cytochrome c-553 = pyruvate + 2 a reduced cytochrome c-553 + 2 H+ (

Unification Links: KEGG:R00476 , Rhea:21264

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC:


Lord72: Lord JM (1972). "Glycolate oxidoreductase in Escherichia coli." Biochim Biophys Acta 1972;267(2);227-37. PMID: 4557653

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sun Oct 4, 2015, biocyc13.