MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateMacromolecule ReactionsPolynucleotide-ReactionsRNA-ReactionstRNA-ReactionstRNA-Charging-Reactions

EC Number:

Enzymes and Genes:

Escherichia coli K-12 substr. MG1655: histidyl-tRNA synthetaseInferred from experiment: hisS

In Pathway: tRNA charging

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: histidine—tRNA ligase

Enzyme Commission Synonyms: histidyl-tRNA synthetase, histidyl-transfer ribonucleate synthetase, histidine translase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -92.58356Inferred by computational analysis [Latendresse13]

Citations: [vonTigerstrom67]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R03655, Rhea:17313

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:, UniProt:RELATED-TO:O32039, UniProt:RELATED-TO:O34459, UniProt:RELATED-TO:O51160, UniProt:RELATED-TO:O58028, UniProt:RELATED-TO:O66522, UniProt:RELATED-TO:O67223, UniProt:RELATED-TO:O82413, UniProt:RELATED-TO:O83647, UniProt:RELATED-TO:O84547, UniProt:RELATED-TO:P07263, UniProt:RELATED-TO:P12081, UniProt:RELATED-TO:P30053, UniProt:RELATED-TO:P43823, UniProt:RELATED-TO:P46696, UniProt:RELATED-TO:P47281, UniProt:RELATED-TO:P51348, UniProt:RELATED-TO:P56455, UniProt:RELATED-TO:P60906, UniProt:RELATED-TO:P75069, UniProt:RELATED-TO:P93422, UniProt:RELATED-TO:Q9CE78, UniProt:RELATED-TO:Q9JUZ9, UniProt:RELATED-TO:Q9PPF4, UniProt:RELATED-TO:Q9X0H5, UniProt:RELATED-TO:Q9Z7P1, UniProt:RELATED-TO:Q9ZDL9, UniProt:RELATED-TO:Q9ZK27, UniProt:RELATED-TO:Q49027, UniProt:RELATED-TO:Q55653, UniProt:RELATED-TO:Q58406, UniProt:RELATED-TO:Q61035


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

vonTigerstrom67: von Tigerstrom M, Tener GM (1967). "Histidyl transfer ribonucleic acid synthetase from bakers' yeast." Can J Biochem 45(7);1067-74. PMID: 6035970

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.5 on Sat Nov 28, 2015, BIOCYC14B.