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MetaCyc Reaction: 6.1.1.21

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Macromolecule Reactions Polynucleotide-Reactions RNA-Reactions tRNA-Reactions tRNA-Charging-Reactions

EC Number: 6.1.1.21

Enzymes and Genes:

Escherichia coli K-12 substr. MG1655 : histidyl-tRNA synthetase Inferred from experiment : hisS

In Pathway: tRNA charging

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: histidine—tRNA ligase

Enzyme Commission Synonyms: histidyl-tRNA synθse, histidyl-transfer ribonucleate synθse, histidine translase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -92.58356 Inferred by computational analysis [Latendresse13]

Citations: [vonTigerstrom67]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R03655 , Rhea:17313

Relationship Links: BRENDA:EC:6.1.1.21 , ENZYME:EC:6.1.1.21 , IUBMB-ExplorEnz:EC:6.1.1.21 , UniProt:RELATED-TO:O32039 , UniProt:RELATED-TO:O34459 , UniProt:RELATED-TO:O51160 , UniProt:RELATED-TO:O58028 , UniProt:RELATED-TO:O66522 , UniProt:RELATED-TO:O67223 , UniProt:RELATED-TO:O82413 , UniProt:RELATED-TO:O83647 , UniProt:RELATED-TO:O84547 , UniProt:RELATED-TO:P07263 , UniProt:RELATED-TO:P12081 , UniProt:RELATED-TO:P30053 , UniProt:RELATED-TO:P43823 , UniProt:RELATED-TO:P46696 , UniProt:RELATED-TO:P47281 , UniProt:RELATED-TO:P51348 , UniProt:RELATED-TO:P56455 , UniProt:RELATED-TO:P60906 , UniProt:RELATED-TO:P75069 , UniProt:RELATED-TO:P93422 , UniProt:RELATED-TO:Q9CE78 , UniProt:RELATED-TO:Q9JUZ9 , UniProt:RELATED-TO:Q9PPF4 , UniProt:RELATED-TO:Q9X0H5 , UniProt:RELATED-TO:Q9Z7P1 , UniProt:RELATED-TO:Q9ZDL9 , UniProt:RELATED-TO:Q9ZK27 , UniProt:RELATED-TO:Q49027 , UniProt:RELATED-TO:Q55653 , UniProt:RELATED-TO:Q58406 , UniProt:RELATED-TO:Q61035


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

vonTigerstrom67: von Tigerstrom M, Tener GM (1967). "Histidyl transfer ribonucleic acid synthetase from bakers' yeast." Can J Biochem 45(7);1067-74. PMID: 6035970


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Mon Aug 3, 2015, biocyc11.