|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions → Composite Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 22.214.171.124
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: nucleoside oxidase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -113.9811 [Latendresse13]
Enzyme Commission Summary:
Other purine and pyrimidine nucleosides (as well as 2'-deoxynucleosides) are substrates, but ribose and nucleotides are not substrates.
The overall reaction takes place in two separate steps, with the 5'-dehydro nucleoside being released from the enzyme to serve as substrate for the second reaction.
The two reactions are:
This enzyme differs from EC 126.96.36.199, nucleoside oxidase (H2O2-forming), as it produces water rather than hydrogen peroxide.
Unification Links: KEGG:R05821
©2014 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493