twitter

MetaCyc Reaction: 2.7.1.77

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.7.1.77

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Instance reaction:
AMP + thymidine = dTMP + adenosine (2.7.1.114)

Enzyme Commission Primary Name: nucleoside phosphotransferase

Enzyme Commission Synonyms: nonspecific nucleoside phosphotransferase, nucleotide:3'-deoxynucleoside 5'-phosphotransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 0.0 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Phenyl phosphate and nucleoside 3'-phosphates can act as donors, although not so well as nucleoside 5'-phosphates. Nucleosides as well as 2'-deoxynucleosides can act as acceptors.

Citations: [Brunngraber67, Prasher82]

Unification Links: KEGG:R07341

Relationship Links: BRENDA:EC:2.7.1.77 , ENZYME:EC:2.7.1.77 , IUBMB-ExplorEnz:EC:2.7.1.77


References

Brunngraber67: Brunngraber EF, Chargaff E (1967). "Purification and properties of a nucleoside phosphotransferase from carrot." J Biol Chem 242(20);4834-40. PMID: 6061424

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Prasher82: Prasher DC, Carr MC, Ives DH, Tsai TC, Frey PA (1982). "Nucleoside phosphotransferase from barley. Characterization and evidence for ping pong kinetics involving phosphoryl enzyme." J Biol Chem 257(9);4931-9. PMID: 6279651


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Mon Aug 3, 2015, biocyc12.