MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Instance reaction:
AMP + thymidine = dTMP + adenosine (

Enzyme Commission Primary Name: nucleoside phosphotransferase

Enzyme Commission Synonyms: nonspecific nucleoside phosphotransferase, nucleotide:3'-deoxynucleoside 5'-phosphotransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 0.0Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Phenyl phosphate and nucleoside 3'-phosphates can act as donors, although not so well as nucleoside 5'-phosphates. Nucleosides as well as 2'-deoxynucleosides can act as acceptors.

Citations: [Brunngraber67, Prasher82]

Unification Links: KEGG:R07341

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


Brunngraber67: Brunngraber EF, Chargaff E (1967). "Purification and properties of a nucleoside phosphotransferase from carrot." J Biol Chem 242(20);4834-40. PMID: 6061424

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Prasher82: Prasher DC, Carr MC, Ives DH, Tsai TC, Frey PA (1982). "Nucleoside phosphotransferase from barley. Characterization and evidence for ping pong kinetics involving phosphoryl enzyme." J Biol Chem 257(9);4931-9. PMID: 6279651

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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