Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 2.7.1.77

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.7.1.77

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Instance reaction:
AMP + thymidine = dTMP + adenosine (2.7.1.114)

Enzyme Commission Primary Name: nucleoside phosphotransferase

Enzyme Commission Synonyms: nonspecific nucleoside phosphotransferase, nucleotide:3'-deoxynucleoside 5'-phosphotransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 0.0 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Phenyl phosphate and nucleoside 3'-phosphates can act as donors, although not so well as nucleoside 5'-phosphates. Nucleosides as well as 2'-deoxynucleosides can act as acceptors.

Citations: [Brunngraber67, Prasher82]

Unification Links: KEGG:R07341

Relationship Links: BRENDA:EC:2.7.1.77 , ENZYME:EC:2.7.1.77 , IUBMB-ExplorEnz:EC:2.7.1.77


References

Brunngraber67: Brunngraber EF, Chargaff E (1967). "Purification and properties of a nucleoside phosphotransferase from carrot." J Biol Chem 242(20);4834-40. PMID: 6061424

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Prasher82: Prasher DC, Carr MC, Ives DH, Tsai TC, Frey PA (1982). "Nucleoside phosphotransferase from barley. Characterization and evidence for ping pong kinetics involving phosphoryl enzyme." J Biol Chem 257(9);4931-9. PMID: 6279651


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Tue Nov 25, 2014, BIOCYC13A.