Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 4.1.1.2

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 4.1.1.2

Enzymes and Genes:
oxalate decarboxylase Inferred from experiment : oxdC ( Bacillus subtilis )

In Pathway: oxalate degradation V

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: oxalate decarboxylase

Enzyme Commission Synonyms: oxalate carboxy-lyase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -4.2717743 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
The enzyme from Bacillus subtilis contains manganese and requires O2 for activity, even though there is no net redox change.

Citations: [Hayaishi56, Tanner00, Tanner01]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R00522 , Rhea:16509

Relationship Links: BRENDA:EC:4.1.1.2 , ENZYME:EC:4.1.1.2 , IUBMB-ExplorEnz:EC:4.1.1.2

Credits:
Revised 23-Jan-2011 by Caspi R , SRI International


References

Hayaishi56: Hayaishi O, Jakoby WB, Ohmura E (1956). "Enzymatic decarboxylation of oxalic acid." J Biol Chem 222(1);435-46. PMID: 13367015

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Tanner00: Tanner A, Bornemann S (2000). "Bacillus subtilis YvrK is an acid-induced oxalate decarboxylase." J Bacteriol 182(18);5271-3. PMID: 10960116

Tanner01: Tanner A, Bowater L, Fairhurst SA, Bornemann S (2001). "Oxalate decarboxylase requires manganese and dioxygen for activity. Overexpression and characterization of Bacillus subtilis YvrK and YoaN." J Biol Chem 276(47);43627-34. PMID: 11546787


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Mon Nov 24, 2014, BIOCYC14B.