MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:

Bacillus subtilis : oxalate decarboxylase Inferred from experiment : oxdC

In Pathway: oxalate degradation V

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: oxalate decarboxylase

Enzyme Commission Synonyms: oxalate carboxy-lyase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -4.2717743 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
The enzyme from Bacillus subtilis contains manganese and requires O2 for activity, even though there is no net redox change.

Citations: [Hayaishi56, Tanner00, Tanner01]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R00522 , Rhea:16509

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC:

Revised 23-Jan-2011 by Caspi R , SRI International


Hayaishi56: Hayaishi O, Jakoby WB, Ohmura E (1956). "Enzymatic decarboxylation of oxalic acid." J Biol Chem 222(1);435-46. PMID: 13367015

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Tanner00: Tanner A, Bornemann S (2000). "Bacillus subtilis YvrK is an acid-induced oxalate decarboxylase." J Bacteriol 182(18);5271-3. PMID: 10960116

Tanner01: Tanner A, Bowater L, Fairhurst SA, Bornemann S (2001). "Oxalate decarboxylase requires manganese and dioxygen for activity. Overexpression and characterization of Bacillus subtilis YvrK and YoaN." J Biol Chem 276(47);43627-34. PMID: 11546787

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sun Oct 4, 2015, biocyc13.