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MetaCyc Reaction: 4.1.1.2

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number: 4.1.1.2

Enzymes and Genes:

Bacillus subtilis: oxalate decarboxylaseInferred from experiment: oxdC

In Pathway: oxalate degradation V

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: oxalate decarboxylase

Enzyme Commission Synonyms: oxalate carboxy-lyase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -4.2717743Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
The enzyme from Bacillus subtilis contains manganese and requires O2 for activity, even though there is no net redox change.

Citations: [Hayaishi56, Tanner00, Tanner01 ]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R00522, Rhea:16509

Relationship Links: BRENDA:EC:4.1.1.2, ENZYME:EC:4.1.1.2, IUBMB-ExplorEnz:EC:4.1.1.2

Credits:
Revised 23-Jan-2011 by Caspi R, SRI International


References

Hayaishi56: Hayaishi O, Jakoby WB, Ohmura E (1956). "Enzymatic decarboxylation of oxalic acid." J Biol Chem 222(1);435-46. PMID: 13367015

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Tanner00: Tanner A, Bornemann S (2000). "Bacillus subtilis YvrK is an acid-induced oxalate decarboxylase." J Bacteriol 182(18);5271-3. PMID: 10960116

Tanner01: Tanner A, Bowater L, Fairhurst SA, Bornemann S (2001). "Oxalate decarboxylase requires manganese and dioxygen for activity. Overexpression and characterization of Bacillus subtilis YvrK and YoaN." J Biol Chem 276(47);43627-34. PMID: 11546787


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Sun May 1, 2016, biocyc14.