Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
twitter

MetaCyc Reaction: 2.3.1.8

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.3.1.8

Enzymes and Genes:
phosphate acetyltransferase Inferred from experiment : pta ( Escherichia coli K-12 substr. MG1655 )
phosphate acetyltransferase Inferred from experiment : eutD ( Escherichia coli K-12 substr. MG1655 )
phosphate acetyltransferase Author statement Inferred by computational analysis : PAT2 ( Chlamydomonas reinhardtii )
phosphate propanoyltransferase Inferred from experiment : pduL ( Salmonella enterica enterica serovar Typhimurium str. LT2 )
phosphate acetyltransferase Inferred from experiment : pta ( Roseovarius nubinhibens ISM )
phosphate acetyltransferase Inferred from experiment : pta ( Clostridium kluyveri )
phosphate acetyltransferase Inferred from experiment ( Dasytricha ruminantium )
phosphate acetyltransferase Inferred from experiment ( Pelobacter acetylenicus )
phosphotransacetylase Inferred from experiment ( Gottschalkia acidurici )
phosphotransacetylase Inferred from experiment : pta ( Lactobacillus sanfranciscensis )
phosphotransacetylase Inferred from experiment ( Fusobacterium nucleatum )
phosphate acetyltransferase Inferred from experiment : pta ( Paracoccus denitrificans NKNIS )
phosphate acetyltransferase Inferred from experiment ( Eubacterium oxidoreducens G41 )
phosphate acetyltransferase Inferred from experiment : pta ( Mycoplasma pneumoniae M129 )
phosphate acetyltransferase Inferred from experiment : pta ( Thermotoga maritima )
phosphate acetyltransferase Inferred from experiment ( Moorella thermoacetica )
phosphotransacetylase Inferred from experiment : pta ( Methanosarcina thermophila )
phosphotransacetylase Inferred from experiment ( [Clostridium] propionicum )
phosphotransacetylase Inferred from experiment : pta ( Clostridium acetobutylicum )

In Pathway: pyruvate fermentation to acetate II , heterolactic fermentation , acetylene degradation , acetate formation from acetyl-CoA I , pyruvate fermentation to acetate IV , lysine fermentation to acetate and butyrate , sulfoacetaldehyde degradation I , mixed acid fermentation , sulfolactate degradation II , gallate degradation III (anaerobic) , methanogenesis from acetate , superpathway of fermentation (Chlamydomonas reinhardtii) , purine nucleobases degradation II (anaerobic)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: phosphate acetyltransferase

Enzyme Commission Synonyms: phosphotransacetylase, phosphoacylase, PTA

Standard Gibbs Free Energy (ΔrG in kcal/mol): -7.2700195 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Also acts with other short-chain acyl-CoAs.

Citations: [STADTMAN52, Bergmeyer63]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R00230 , Rhea:19521

Relationship Links: BRENDA:EC:2.3.1.8 , ENZYME:EC:2.3.1.8 , IUBMB-ExplorEnz:EC:2.3.1.8 , UniProt:RELATED-TO:P0A9M8 , UniProt:RELATED-TO:P38503 , UniProt:RELATED-TO:P45107 , UniProt:RELATED-TO:P47541 , UniProt:RELATED-TO:P73662 , UniProt:RELATED-TO:P75359 , UniProt:RELATED-TO:Q9CF22 , UniProt:RELATED-TO:Q9PPL9 , UniProt:RELATED-TO:Q9RY77


References

Bergmeyer63: Bergmeyer, H.U., Holz, G., Klotzsch, H., Lang, G. (1963). "[Phosphotransacetylase from Clostridium kluyveri. Culture of the bacterium, isolation, crystallization and properties of the enzyme.]." Biochem Z 338;114-21. PMID: 14087284

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

STADTMAN52: STADTMAN ER (1952). "The purification and properties of phosphotransacetylase." J Biol Chem 196(2);527-34. PMID: 12980995


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Thu Nov 27, 2014, biocyc12.