MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:

Rhodococcus rhodochrous: nitrile hydrataseInferred from experiment: nhhA, nhhB

In Pathway: aldoxime degradation

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: nitrile hydratase

Enzyme Commission Synonyms: nitrilase (ambiguous), 3-cyanopyridine hydratase, NHase, L-NHase, H-NHase, acrylonitrile hydratase, aliphatic nitrile hydratase, nitrile hydro-lyase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 4.977001Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Acts on short-chain aliphatic nitriles, converting them into the corresponding amides. Does not act on these amides or on aromatic nitriles. cf. EC nitrilase.

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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