Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
twitter

MetaCyc Reaction: 1.1.1.4

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number: 1.1.1.4

Enzymes and Genes:

Paenibacillus polymyxa: (R-acetoin forming)-(R,R)-2,3-butanediol dehydrogenaseInferred from experiment
Saccharomyces cerevisiae: (R,R)-butanediol dehydrogenaseInferred from experiment: BDH1

In Pathway: (R,R)-butanediol biosynthesis, (R,R)-butanediol degradation

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: (R,R)-butanediol dehydrogenase

Enzyme Commission Synonyms: butyleneglycol dehydrogenase, D-butanediol dehydrogenase, D-(-)-butanediol dehydrogenase, butylene glycol dehydrogenase, diacetyl (acetoin) reductase, D-aminopropanol dehydrogenase, 1-amino-2-propanol dehydrogenase, 2,3-butanediol dehydrogenase, D-1-amino-2-propanol dehydrogenase, (R)-diacetyl reductase, (R)-2,3-butanediol dehydrogenase, D-1-amino-2-propanol:NAD+ oxidoreductase, 1-amino-2-propanol oxidoreductase, aminopropanol oxidoreductase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 1.0817871Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Also converts diacetyl into acetoin with NADH as reductant.

Citations: [Strecker54, Taylor60]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R02946, Rhea:24340

Relationship Links: BRENDA:EC:1.1.1.4, ENZYME:EC:1.1.1.4, IUBMB-ExplorEnz:EC:1.1.1.4, UniProt:RELATED-TO:Q9CH42, UniProt:RELATED-TO:Q04520

Credits:
Revised 11-Sep-2012 by Caspi R, SRI International


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Strecker54: Strecker, H.J., Harary, I. (1954). "Bacterial butylene glycol dehydrogenase and diacetyl reductase." J Biol Chem 211(1);263-70. PMID: 13211662

Taylor60: Taylor, MB, Juni, E (1960). "Stereoisomeric specificities of 2,3-butanediol dehydrogenases." Biochim Biophys Acta 39;448-57. PMID: 13837186


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Tue May 3, 2016, biocyc13.