|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 22.214.171.124
Enzymes and Genes:
|Methanocaldococcus jannaschii:||6-deoxy-5-ketofructose 1-phosphate synthase: MJ1585|
In Pathway: 3-dehydroquinate biosynthesis II (archaea)
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: 6-deoxy-5-ketofructose 1-phosphate synthase
Enzyme Commission Synonyms: DKFP synthase, MJ1585 (gene name)
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): 0.13647461 [Latendresse13]
Enzyme Commission Summary:
The enzyme plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. The enzyme can also catalyse the reaction of EC 126.96.36.199, fructose-bisphosphate aldolase.
Unification Links: Rhea:31914
White06: White RH, Xu H (2006). "Methylglyoxal is an intermediate in the biosynthesis of 6-deoxy-5-ketofructose-1-phosphate: a precursor for aromatic amino acid biosynthesis in Methanocaldococcus jannaschii." Biochemistry 45(40);12366-79. PMID: 17014089
©2015 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493