|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 220.127.116.11
Enzymes and Genes:
|Methanocaldococcus jannaschii :||6-deoxy-5-ketofructose 1-phosphate synthase
In Pathway: 3-dehydroquinate biosynthesis II (archaea)
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: 6-deoxy-5-ketofructose 1-phosphate synthase
Enzyme Commission Synonyms: DKFP synthase, MJ1585 (gene name)
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): 0.13647461 [Latendresse13]
Enzyme Commission Summary:
The enzyme plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. The enzyme can also catalyse the reaction of EC 18.104.22.168, fructose-bisphosphate aldolase.
Unification Links: Rhea:31914
White06: White RH, Xu H (2006). "Methylglyoxal is an intermediate in the biosynthesis of 6-deoxy-5-ketofructose-1-phosphate: a precursor for aromatic amino acid biosynthesis in Methanocaldococcus jannaschii." Biochemistry 45(40);12366-79. PMID: 17014089
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