Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: [no EC number assigned]

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Mass balance status: Marked as unbalanced.

Summary:
The substrate, fatty acyl-CoA is at least 18-carbons (C18) in length. The product, very long chain fatty acyl-CoA is longer than C18 in length and up to C32 in length. The reaction adds a C2 to the substrate and extends its length by 2 carbons each reaction. Different fatty acid elongases have different substrate specificities, i.e. they catalyze substrates having different carbon chain length and different degrees of saturation [Millar99].


References

Millar99: Millar AA, Clemens S, Zachgo S, Giblin EM, Taylor DC, Kunst L (1999). "CUT1, an Arabidopsis gene required for cuticular wax biosynthesis and pollen fertility, encodes a very-long-chain fatty acid condensing enzyme." Plant Cell 1999;11(5);825-38. PMID: 10330468


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Thu Nov 27, 2014, BIOCYC13A.