|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 22.214.171.124
Enzymes and Genes:
|Zea mays:||polyamine oxidase (propane-1,3-diamine forming): MPAO|
Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.
Mass balance status: Balanced.
Enzyme Commission Primary Name: polyamine oxidase (propane-1,3-diamine-forming)
Enzyme Commission Synonyms: MPAO, maize PAO
Taxonomic Range: Viridiplantae
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -22.204773 [Latendresse13]
Enzyme Commission Summary:
A flavoprotein (FAD). This enzyme, found in the cell walls of monocot plants, oxidizes spermine and spermidine at the four-carbon side of their secondary amine, forming propane-1,3-diamine and hydrogen peroxide [Tavladoraki98]. As the products cannot be converted directly to other polyamines, this class of polyamine oxidases is considered to be involved in the terminal catabolism of polyamines. The enzyme also accepts N1-acetylspermine as substrate, but is quickly inactivated during the reaction [Sebela01].
Unification Links: Rhea:25996
Sebela01: Sebela M, Radova A, Angelini R, Tavladoraki P, Frebort , Pec P (2001). "FAD-containing polyamine oxidases: a timely challenge for researchers in biochemistry and physiology of plants." Plant Sci 160(2);197-207. PMID: 11164591
Tavladoraki98: Tavladoraki P, Schinina ME, Cecconi F, Di Agostino S, Manera F, Rea G, Mariottini P, Federico R, Angelini R (1998). "Maize polyamine oxidase: primary structure from protein and cDNA sequencing." FEBS Lett 426(1);62-6. PMID: 9598979
©2016 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493