|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 1.14.13.cq
Enzymes and Genes:
|Petunia x hybrida :||acyl-CoA ω-hydroxylase
In Pathway: stigma estolide biosynthesis
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: long-chain acyl-CoA ω-monooxygenase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -88.65057 [Latendresse13]
Enzyme Commission Summary:
The enzymes from solanaceous plants are involved in the biosynthesis of stigmatic estolide, a lipid-based polyester that forms a major component of the exudate. The enzyme from the yeast Starmerella bombicola can also hydroxylate the (ω-1) position.
Han10: Han J, Clement JM, Li J, King A, Ng S, Jaworski JG (2010). "The cytochrome P450 CYP86A22 is a fatty acyl-CoA omega-hydroxylase essential for Estolide synthesis in the stigma of Petunia hybrida." J Biol Chem 285(6);3986-96. PMID: 19940120
Huang14: Huang FC, Peter A, Schwab W (2014). "Expression and characterization of CYP52 genes involved in the biosynthesis of sophorolipid and alkane metabolism from Starmerella bombicola." Appl Environ Microbiol 80(2);766-76. PMID: 24242247
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