MetaCyc Reaction: 1.14.13.cq

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 1.14.13.cq

Enzymes and Genes:

Petunia x hybrida : acyl-CoA ω-hydroxylase Inferred from experiment : CYP86A22

In Pathway: stigma estolide biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: long-chain acyl-CoA ω-monooxygenase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -88.65057 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
The enzymes from solanaceous plants are involved in the biosynthesis of stigmatic estolide, a lipid-based polyester that forms a major component of the exudate. The enzyme from the yeast Starmerella bombicola can also hydroxylate the (ω-1) position.

Citations: [Han10, Huang14]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Created 21-Nov-2014 by Caspi R , SRI International


Han10: Han J, Clement JM, Li J, King A, Ng S, Jaworski JG (2010). "The cytochrome P450 CYP86A22 is a fatty acyl-CoA omega-hydroxylase essential for Estolide synthesis in the stigma of Petunia hybrida." J Biol Chem 285(6);3986-96. PMID: 19940120

Huang14: Huang FC, Peter A, Schwab W (2014). "Expression and characterization of CYP52 genes involved in the biosynthesis of sophorolipid and alkane metabolism from Starmerella bombicola." Appl Environ Microbiol 80(2);766-76. PMID: 24242247

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sat Oct 10, 2015, biocyc13.