Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites MAYBE down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites MAYBE down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites MAYBE down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites MAYBE down
12/28 - 12/31
for maintenance.
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MetaCyc Reaction: 1.14.13.-

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 1.14.13.-

Enzymes and Genes:
oleate omega-hydroxylase Inferred from experiment : CYP704B2 ( Oryza sativa Japonica Group )
fatty acid ω-hydroxylase Inferred from experiment : CYP86A1 ( Arabidopsis thaliana col )
fatty acid ω-hydroxylase Inferred from experiment : CYP94C1 ( Arabidopsis thaliana col )
fatty acid ω-hydroxylase Inferred from experiment ( Glycine max )
fatty acid ω-hydroxylase Inferred from experiment : CYP86A8 ( Arabidopsis thaliana col )
long-chain fatty acid ω-hydroxylase : CYP704B1 ( Arabidopsis thaliana col )
cytochrome P450 monooxygenase CYP52M1 : CYP52M1 ( Starmerella bombicola )

In Pathway: cutin biosynthesis , suberin monomers biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 1.14.13 -- With NADH or NADPH as one donor, and incorporation of one atom of oxygen

Standard Gibbs Free Energy (ΔrG in kcal/mol): -88.65048 Inferred by computational analysis [Latendresse13]

Gene-Reaction Schematic: ?

Instance reaction of [a fatty acid + NADPH + oxygen + H+ → an in-chain hydroxy fatty acid + NADP+ + H2O] (1.14.13.-):
i1: laurate + NADPH + oxygen + H+ → ω-1 laurate + NADP+ + H2O (1.14.13.-)

Instance reactions of [a fatty acid + NADPH + oxygen + H+ → an ω-hydroxy fatty acid + NADP+ + H2O] (1.14.13.-):
i2: 9,10-epoxystearate + NADPH + H+ + oxygen → 9,10-epoxy-18-hydroxystearate + NADP+ + H2O (1.14.13.-)

i3: oleate + NADPH + oxygen + H+ → 18-hydroxyoleate + NADP+ + H2O (1.14.13.-)
i4: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + NADPH + H+ + oxygen = 22-hydroxydocosahexaenoate + NADP+ + H2O (1.14.13.cl)

i5: (9R,10S)-dihydroxystearate + NADPH + H+ + oxygen → 9,10,18-trihydroxystearate + NADP+ + H2O (1.14.13.-)

i6: behenate + NADPH + oxygen + H+ → 22-hydroxydocosanoate + NADP+ + H2O (1.14.13.-)

i7: palmitate + NADPH + H+ + oxygen → 16-hydroxypalmitate + NADP+ + H2O (1.14.13.-)

i8: laurate + NADPH + oxygen + H+ → ω-hydroxylaurate + NADP+ + H2O (1.14.13.-)

Credits:
Revised 24-Jul-2014 by Fulcher CA , SRI International


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sat Dec 27, 2014, biocyc11.