|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 126.96.36.199
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: glycine N-phenylacetyltransferase
Enzyme Commission Synonyms: arylacetyl-CoA N-acyltransferase, arylacetyltransferase, GAT (gene name)
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -5.0441284 [Latendresse13]
Enzyme Commission Summary:
Not identical with EC 188.8.131.52 (glycine N-acyltransferase). This enzyme was purified from bovine liver mitochondria. L-asparagine, L-glutamine and L-arginine are also substrates, but have higher Km values.
Kelley90: Kelley M, Vessey DA (1990). "The effects of ions on the conjugation of xenobiotics by the aralkyl-CoA and arylacetyl-CoA N-acyltransferases from bovine liver mitochondria." J Biochem Toxicol 5(2);125-35. PMID: 2283662
Nandi79: Nandi DL, Lucas SV, Webster LT (1979). "Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization." J Biol Chem 254(15);7230-7. PMID: 457678
Vessey98: Vessey DA, Lau E (1998). "Determination of the sequence of the arylacetyl acyl-CoA:amino acid N-acyltransferase from bovine liver mitochondria and its homology to the aralkyl acyl-CoA:amino acid N-acyltransferase." J Biochem Mol Toxicol 12(5);275-9. PMID: 9664233
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