Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 3.6.1.14

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.6.1.14

Enzymes and Genes:
diphosphoinositol polyphosphate phosphohydrolase 3α Inferred from experiment : NUDT10 ( Homo sapiens )
diphosphoinositol polyphosphate phosphohydrolase 3β Inferred from experiment : NUDT11 ( Homo sapiens )

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: adenosine-tetraphosphatase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -101.96472 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Also acts on inosine tetraphosphate and tripolyphosphate but shows little or no activity with other nucleotides or polyphosphates.

Citations: [Leslie02, Small66]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:3.6.1.14 , ENZYME:EC:3.6.1.14 , IUBMB-ExplorEnz:EC:3.6.1.14

Credits:
Created 29-Oct-2009 by Caspi R , SRI International


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Leslie02: Leslie NR, McLennan AG, Safrany ST (2002). "Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases." BMC Biochem 3;20. PMID: 12121577

Small66: Small GD, Cooper C (1966). "Purification and properties of nucleoside tetraphosphate hydrolase from rabbit muscle." Biochemistry 5(1);14-26. PMID: 4287215


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sun Nov 23, 2014, BIOCYC14B.