MetaCyc Reaction: 1.1.1.-

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 1.1.1.-

Enzymes and Genes:

Geobacillus stearothermophilus : diacetyl (acetoin) reductase Inferred from experiment
Klebsiella pneumoniae : [(R)-acetoin forming]-meso-2,3-butanediol dehydrogenase Inferred from experiment : budC
Serratia marcescens H30 : meso-butanediol dehydrogenase [(R)-acetoin-forming] Inferred from experiment : budC

In Pathway: meso-butanediol biosynthesis I

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 1.1.1 -- With NAD(+) or NADP(+) as acceptor

Standard Gibbs Free Energy (ΔrG in kcal/mol): 1.0817871 Inferred by computational analysis [Latendresse13]

Citations: [Ui97]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Instance reaction of [acetoin + NAD+ ← diacetyl + NADH + H+] (1.1.1.-):
i1: (S)-acetoin + NAD+ ← diacetyl + NADH + H+ (

Created 23-Nov-2009 by Caspi R , SRI International


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Ui97: Ui, S., Okajima, Y., Mimura, A., Kanai, H., Kobayashi, T., Kudo, T. (1997). "Sequence analysis of the gene for and characterization of D-acetoin forming meso-2,3-butanediol dehydrogenase of Klebsiella pneumoniae expressed in Escherichia coli." J. Ferment. Bioeng. 83: 32-37.

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sun May 24, 2015, biocyc12.