MetaCyc Reaction: 1.1.1.-

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number: 1.1.1.-

Enzymes and Genes:

Geobacillus stearothermophilus: diacetyl (acetoin) reductaseInferred from experiment
Klebsiella pneumoniae: [(R)-acetoin forming]-meso-2,3-butanediol dehydrogenaseInferred from experiment: budC
Serratia marcescens H30: meso-butanediol dehydrogenase [(R)-acetoin-forming]Inferred from experiment: budC

In Pathway: meso-butanediol biosynthesis I

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 1.1.1 -- With NAD(+) or NADP(+) as acceptor

Standard Gibbs Free Energy (ΔrG in kcal/mol): 1.0817871Inferred by computational analysis [Latendresse13]

Citations: [Ui97]

Gene-Reaction Schematic

Gene-Reaction Schematic

Instance reaction of [acetoin + NAD+ ← diacetyl + NADH + H+] (1.1.1.-):
i1: (S)-acetoin + NAD+ ← diacetyl + NADH + H+ (

Created 23-Nov-2009 by Caspi R, SRI International


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Ui97: Ui, S., Okajima, Y., Mimura, A., Kanai, H., Kobayashi, T., Kudo, T. (1997). "Sequence analysis of the gene for and characterization of D-acetoin forming meso-2,3-butanediol dehydrogenase of Klebsiella pneumoniae expressed in Escherichia coli." J. Ferment. Bioeng. 83: 32-37.

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Wed Nov 25, 2015, biocyc12.