|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 22.214.171.124
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balance undetermined; a substrate lacks a chemical formula
Enzyme Commission Primary Name: nitroalkane oxidase
Enzyme Commission Synonyms: nitroethane oxidase, NAO, nitroethane:oxygen oxidoreductase
Taxonomic Range: Fungi
Enzyme Commission Summary:
Has an absolute requirement for FAD [Fitzpatrick05]. While nitroethane may be the physiological substrate [Kido78], the enzyme also acts on several other nitroalkanes, including 1-nitropropane, 2-nitropropane, 1-nitrobutane, 1-nitropentane, 1-nitrohexane, nitrocyclohexane and some nitroalkanols [Fitzpatrick05].
Daubner02: Daubner SC, Gadda G, Valley MP, Fitzpatrick PF (2002). "Cloning of nitroalkane oxidase from Fusarium oxysporum identifies a new member of the acyl-CoA dehydrogenase superfamily." Proc Natl Acad Sci U S A 99(5);2702-7. PMID: 11867731
Fitzpatrick05: Fitzpatrick PF, Orville AM, Nagpal A, Valley MP (2005). "Nitroalkane oxidase, a carbanion-forming flavoprotein homologous to acyl-CoA dehydrogenase." Arch Biochem Biophys 433(1);157-65. PMID: 15581574
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