|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 22.214.171.124
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balance undetermined; a substrate lacks a chemical formula
Enzyme Commission Primary Name: nitroalkane oxidase
Enzyme Commission Synonyms: nitroethane oxidase, NAO, nitroethane:oxygen oxidoreductase
Taxonomic Range: Fungi
Enzyme Commission Summary:
Has an absolute requirement for FAD [Fitzpatrick05]. While nitroethane may be the physiological substrate [Kido78], the enzyme also acts on several other nitroalkanes, including 1-nitropropane, 2-nitropropane, 1-nitrobutane, 1-nitropentane, 1-nitrohexane, nitrocyclohexane and some nitroalkanols [Fitzpatrick05].
Daubner02: Daubner SC, Gadda G, Valley MP, Fitzpatrick PF (2002). "Cloning of nitroalkane oxidase from Fusarium oxysporum identifies a new member of the acyl-CoA dehydrogenase superfamily." Proc Natl Acad Sci U S A 99(5);2702-7. PMID: 11867731
Fitzpatrick05: Fitzpatrick PF, Orville AM, Nagpal A, Valley MP (2005). "Nitroalkane oxidase, a carbanion-forming flavoprotein homologous to acyl-CoA dehydrogenase." Arch Biochem Biophys 433(1);157-65. PMID: 15581574
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