MetaCyc Reaction: [no EC number assigned]

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

Enzymes and Genes:

Arabidopsis thaliana col: ζ-carotene desaturaseInferred from experiment: ZDS
Zea mays: ζ-carotene desaturaseInferred from experiment: ZDS

Sub-reaction of: 9,9'-di-cis-ζ-carotene + 2 an electron-transfer quinone = prolycopene + 2 an electron-transfer quinol

In Pathway: trans-lycopene biosynthesis II (plants)

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Standard Gibbs Free Energy (ΔrG in kcal/mol): 14.177795Inferred by computational analysis [Latendresse13]

This enzyme is involved in carotenoid biosynthesis in plants and cyanobacteria.

This is one of two reactions catalyzed by 9,9'-dicis-ζ-carotene desaturase.

The overall reaction is

9,9'-di-cis-ζ-carotene + 2 an electron-transfer quinone = prolycopene + 2 an electron-transfer quinol

Citations: [Albrecht96, Josse00, Breitenbach99, Breitenbach05]

Gene-Reaction Schematic

Gene-Reaction Schematic

Created 30-Mar-2010 by Caspi R, SRI International


Albrecht96: Albrecht M, Linden H, Sandmann G (1996). "Biochemical characterization of purified zeta-carotene desaturase from Anabaena PCC 7120 after expression in Escherichia coli." Eur J Biochem 236(1);115-20. PMID: 8617254

Breitenbach05: Breitenbach J, Sandmann G (2005). "zeta-Carotene cis isomers as products and substrates in the plant poly-cis carotenoid biosynthetic pathway to lycopene." Planta 220(5);785-93. PMID: 15503129

Breitenbach99: Breitenbach J, Kuntz M, Takaichi S, Sandmann G (1999). "Catalytic properties of an expressed and purified higher plant type zeta-carotene desaturase from Capsicum annuum." Eur J Biochem 265(1);376-83. PMID: 10491195

Josse00: Josse EM, Simkin AJ, Gaffe J, Laboure AM, Kuntz M, Carol P (2000). "A plastid terminal oxidase associated with carotenoid desaturation during chromoplast differentiation." Plant Physiol 123(4);1427-36. PMID: 10938359

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.5 on Mon Nov 30, 2015, BIOCYC14B.