MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:

Arabidopsis thaliana col: geranylgeranyl-diphosphate all-trans-nonaprenyl diphosphate synthaseInferred from experiment: SPS2
geranylgeranyl-diphosphate all-trans-nonaprenyl diphosphate synthaseInferred from experiment: SPS1

In Pathway: nonaprenyl diphosphate biosynthesis II

Supersedes EC number:

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: all-trans-nonaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]

Enzyme Commission Synonyms: nonaprenyl diphosphate synthase (ambiguous), solanesyl diphosphate synthase (ambiguous), At-SPS2, At-SPS1, SPS1, SPS2

Standard Gibbs Free Energy (ΔrG in kcal/mol): -64.99988Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Geranylgeranyl diphosphate is preferred over (2E,6E)-farnesyl diphosphate as allylic substrate [Hirooka03]. Arabidopsis thaliana possesses two alleles - AtSPS2 supplies the precursor of the plastoquinone side-chain, while At-SPS1 contributes to the biosynthesis of the ubiquinone side-chain [Hirooka05].

Citations: [Jun04]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R09251, Rhea:27594

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:

Created 07-Jun-2010 by Caspi R, SRI International


Hirooka03: Hirooka K, Bamba T, Fukusaki E, Kobayashi A (2003). "Cloning and kinetic characterization of Arabidopsis thaliana solanesyl diphosphate synthase." Biochem J 370(Pt 2);679-86. PMID: 12437513

Hirooka05: Hirooka K, Izumi Y, An CI, Nakazawa Y, Fukusaki E, Kobayashi A (2005). "Functional analysis of two solanesyl diphosphate synthases from Arabidopsis thaliana." Biosci Biotechnol Biochem 69(3);592-601. PMID: 15784989

Jun04: Jun L, Saiki R, Tatsumi K, Nakagawa T, Kawamukai M (2004). "Identification and subcellular localization of two solanesyl diphosphate synthases from Arabidopsis thaliana." Plant Cell Physiol 45(12);1882-8. PMID: 15653808

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Sat Nov 28, 2015, biocyc13.