|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 184.108.40.206
Enzymes and Genes:
|Scutellaria baicalensis:||baicalin-β-D-glucuronidase: SGUS|
|Scutellaria viscidula:||baicalin β-D-glucuronidase|
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.
Mass balance status: Balanced.
Enzyme Commission Primary Name: baicalin-β-D-glucuronidase
Enzyme Commission Synonyms: baicalinase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -3.1129913 [Latendresse13]
Enzyme Commission Summary:
The enzyme also hydrolyses wogonin 7-O-β-D-glucuronide and oroxylin 7-O-β-D-glucuronide with lower efficiency [Morimoto95]. Neglegible activity with p-nitrophenyl-β-D-glucuronide [Zhang05].
Unification Links: Rhea:28130
Ikegami95: Ikegami F, Matsunae K, Hisamitsu M, Kurihara T, Yamamoto T, Murakoshi I (1995). "Purification and properties of a plant beta-D-glucuronidase form Scutellaria root." Biol Pharm Bull 18(11);1531-4. PMID: 8593473
Morimoto95: Morimoto, S., Harioka, T., Shoyama, Y. (1995). "Purification and characterization of flavone-specific β-glucuronidase from callus cultures of Scutellaria baicalensis Georgi." Planta 195:535-540.
Zhang05: Zhang, C., Hang, Y., Chen, J., Liang, X. (2005). "Purification and characterization of baicalin-β-D-glucuronidase hydrolyzing baicalin to baicalein from fresh roots of Scutellaria viscidula Bge." Proc. Biochem. 40:1911-1915.
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