Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: [no EC number assigned]

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

Sub-reaction of:
1.1.3.39: adenosine + 2 oxygen + H2O → adenin-9-yl riburonosate + 2 hydrogen peroxide + H+

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Standard Gibbs Free Energy (ΔrG in kcal/mol): -51.489998 Inferred by computational analysis [Latendresse13]

Summary:
This is one of the two reactions catalyzed by nucleoside:oxygen 5'-oxidoreductase (H2O2-forming), EC 1.1.3.39.

(1) adenosine + oxygen = 5'-dehydroadenosine + hydrogen peroxide

(2) 5'-dehydroadenosine + oxygen + H2O = adenin-9-yl riburonosate + hydrogen peroxide + H+

5'-dehydro nucleosides are released from the enzyme after the completion of the first reaction, and serve as substrates for the second reaction.

The overall reaction is:

adenosine + 2 oxygen + H2O → adenin-9-yl riburonosate + 2 hydrogen peroxide + H+

Unification Links: KEGG:R05696 , Rhea:18185

Credits:
Created 28-Oct-2010 by Caspi R , SRI International


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Thu Nov 27, 2014, BIOCYC14A.