MetaCyc Reaction: [no EC number assigned]

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

Sub-reaction of: adenosine + 2 oxygen + H2O → adenin-9-yl riburonosate + 2 hydrogen peroxide + H+

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Standard Gibbs Free Energy (ΔrG in kcal/mol): -51.489998 Inferred by computational analysis [Latendresse13]

This is one of the two reactions catalyzed by nucleoside:oxygen 5'-oxidoreductase (H2O2-forming), EC

(1) adenosine + oxygen → 5'-dehydroadenosine + hydrogen peroxide

(2) 5'-dehydroadenosine + oxygen + H2O → adenin-9-yl riburonosate + hydrogen peroxide + H+

5'-dehydro nucleosides are released from the enzyme after the completion of the first reaction, and serve as substrates for the second reaction.

The overall reaction is:

adenosine + 2 oxygen + H2O → adenin-9-yl riburonosate + 2 hydrogen peroxide + H+

Unification Links: KEGG:R05696 , Rhea:18185

Created 28-Oct-2010 by Caspi R , SRI International


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sun Oct 4, 2015, biocyc13.