MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:

Escherichia coli K-12 substr. MG1655: 2,3-dihydroxyphenylpropionate 1,2-dioxygenaseInferred from experiment: mhpB

In Pathway: cinnamate and 3-hydroxycinnamate degradation to 2-oxopent-4-enoate

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 3-carboxyethylcatechol 2,3-dioxygenase

Enzyme Commission Synonyms: 2,3-dihydroxy-β-phenylpropionic dioxygenase, 2,3-dihydroxy-β-phenylpropionate oxygenase, 3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -69.33823Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
An iron protein. This enzyme catalyses a step in the pathway of phenylpropanoid compounds degradation.

Citations: [Dagley65, Diaz98]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R06788, Rhea:25054

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:

Created 17-Jan-2011 by Caspi R, SRI International


Dagley65: Dagley S, Chapman PJ, Gibson DT (1965). "The metabolism of beta-phenylpropionic acid by an Achromobacter." Biochem J 97(3);643-50. PMID: 5881653

Diaz98: Diaz E, Ferrandez A, Garcia JL (1998). "Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12." J Bacteriol 1998;180(11);2915-23. PMID: 9603882

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Sun Nov 29, 2015, biocyc12.