Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 1.13.11.16

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 1.13.11.16

Enzymes and Genes:
2,3-dihydroxyphenylpropionate 1,2-dioxygenase Inferred from experiment : mhpB ( Escherichia coli K-12 substr. MG1655 )

In Pathway: cinnamate and 3-hydroxycinnamate degradation to 2-oxopent-4-enoate

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 3-carboxyethylcatechol 2,3-dioxygenase

Enzyme Commission Synonyms: 2,3-dihydroxy-β-phenylpropionic dioxygenase, 2,3-dihydroxy-β-phenylpropionate oxygenase, 3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -69.33823 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
An iron protein. This enzyme catalyses a step in the pathway of phenylpropanoid compounds degradation.

Citations: [Dagley65, Diaz98]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R06788 , Rhea:25054

Relationship Links: BRENDA:EC:1.13.11.16 , ENZYME:EC:1.13.11.16 , IUBMB-ExplorEnz:EC:1.13.11.16

Credits:
Created 17-Jan-2011 by Caspi R , SRI International


References

Dagley65: Dagley S, Chapman PJ, Gibson DT (1965). "The metabolism of beta-phenylpropionic acid by an Achromobacter." Biochem J 97(3);643-50. PMID: 5881653

Diaz98: Diaz E, Ferrandez A, Garcia JL (1998). "Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12." J Bacteriol 1998;180(11);2915-23. PMID: 9603882

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sat Nov 22, 2014, BIOCYC13A.