Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 2.4.1.173

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.4.1.173

Enzymes and Genes:
3β-hydroxy sterol glucosyltransferase Inferred from experiment : UGT80A2 ( Arabidopsis thaliana col )
3β-hydroxy sterol glucosyltransferase Inferred from experiment : SGTL1 ( Withania somnifera )

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: sterol 3β-glucosyltransferase

Enzyme Commission Synonyms: UDPG:sterol glucosyltransferase, UDP-glucose-sterol β-glucosyltransferase, sterol:UDPG glucosyltransferase, UDPG-SGTase, uridine diphosphoglucose-poriferasterol glucosyltransferase, uridine diphosphoglucose-sterol glucosyltransferase, sterol glucosyltransferase, sterol-β-D-glucosyltransferase, UDP-glucose-sterol glucosyltransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 6.8975983 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Not identical with EC 2.4.1.192 (nuatigenin 3β-glucosyltransferase) or EC 2.4.1.193 (sarsapogenin 3β-glucosyltransferase).

Citations: [Sharma07, MurakamiMurofus89]

Gene-Reaction Schematic: ?

Instance reaction of [UDP-α-D-glucose + a sterol = UDP + an O-glucosylsterol + H+] (2.4.1.173):
i1: UDP-α-D-glucose + solasodine = UDP + solasodine 3-O-β-D-glucopyranoside + H+ (2.4.1.173)

Relationship Links: BRENDA:EC:2.4.1.173 , ENZYME:EC:2.4.1.173 , IUBMB-ExplorEnz:EC:2.4.1.173

Credits:
Created 04-Feb-2011 by Dreher KA , TAIR


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

MurakamiMurofus89: Murakami-Murofushi K, Ohta J (1989). "Expression of UDP-glucose: poriferasterol glucosyltransferase in the process of differentiation of a true slime mold, Physarum polycephalum." Biochim Biophys Acta 992(3);412-5. PMID: 2528379

Sharma07: Sharma LK, Madina BR, Chaturvedi P, Sangwan RS, Tuli R (2007). "Molecular cloning and characterization of one member of 3beta-hydroxy sterol glucosyltransferase gene family in Withania somnifera." Arch Biochem Biophys 460(1);48-55. PMID: 17324374


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Thu Nov 27, 2014, BIOCYC14B.