|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 220.127.116.11
Enzymes and Genes:
|Arabidopsis thaliana col:||3β-hydroxy sterol glucosyltransferase: UGT80A2|
|Withania somnifera:||3β-hydroxy sterol glucosyltransferase: SGTL1|
Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: sterol 3β-glucosyltransferase
Enzyme Commission Synonyms: UDPG:sterol glucosyltransferase, UDP-glucose-sterol β-glucosyltransferase, sterol:UDPG glucosyltransferase, UDPG-SGTase, uridine diphosphoglucose-poriferasterol glucosyltransferase, uridine diphosphoglucose-sterol glucosyltransferase, sterol glucosyltransferase, sterol-β-D-glucosyltransferase, UDP-glucose-sterol glucosyltransferase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): 6.8975983 [Latendresse13]
Instance reactions of [UDP-α-D-glucose + a sterol = UDP + a sterol 3-β-D-glucoside + H+] (18.104.22.168):
i1: UDP-α-D-glucose + ergosterol = ergosterol 3-O-β-D-glucoside + UDP + H+ (22.214.171.124)
i2: UDP-α-D-glucose + cholesterol = UDP + cholesteryl-β-D-glucoside + H+ (126.96.36.199)
i3: UDP-α-D-glucose + solasodine = UDP + solasodine 3-O-β-D-glucoside + H+ (188.8.131.52)
MurakamiMurofus89: Murakami-Murofushi K, Ohta J (1989). "Expression of UDP-glucose: poriferasterol glucosyltransferase in the process of differentiation of a true slime mold, Physarum polycephalum." Biochim Biophys Acta 992(3);412-5. PMID: 2528379
Sharma07: Sharma LK, Madina BR, Chaturvedi P, Sangwan RS, Tuli R (2007). "Molecular cloning and characterization of one member of 3beta-hydroxy sterol glucosyltransferase gene family in Withania somnifera." Arch Biochem Biophys 460(1);48-55. PMID: 17324374
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