Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
twitter

MetaCyc Reaction: 2.4.1.173

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.4.1.173

Enzymes and Genes:
3β-hydroxy sterol glucosyltransferase Inferred from experiment : UGT80A2 ( Arabidopsis thaliana col )
3β-hydroxy sterol glucosyltransferase Inferred from experiment : SGTL1 ( Withania somnifera )

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: sterol 3β-glucosyltransferase

Enzyme Commission Synonyms: UDPG:sterol glucosyltransferase, UDP-glucose-sterol β-glucosyltransferase, sterol:UDPG glucosyltransferase, UDPG-SGTase, uridine diphosphoglucose-poriferasterol glucosyltransferase, uridine diphosphoglucose-sterol glucosyltransferase, sterol glucosyltransferase, sterol-β-D-glucosyltransferase, UDP-glucose-sterol glucosyltransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 6.8975677 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Not identical with EC 2.4.1.192 (nuatigenin 3β-glucosyltransferase) or EC 2.4.1.193 (sarsapogenin 3β-glucosyltransferase).

Citations: [Sharma07, MurakamiMurofus89]

Gene-Reaction Schematic: ?

Instance reaction of [UDP-α-D-glucose + a sterol = UDP + an O-glucosylsterol + H+] (2.4.1.173):
i1: UDP-α-D-glucose + solasodine = UDP + solasodine 3-O-β-D-glucopyranoside + H+ (2.4.1.173)

Relationship Links: BRENDA:EC:2.4.1.173 , ENZYME:EC:2.4.1.173 , IUBMB-ExplorEnz:EC:2.4.1.173

Credits:
Created 04-Feb-2011 by Dreher KA , TAIR


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

MurakamiMurofus89: Murakami-Murofushi K, Ohta J (1989). "Expression of UDP-glucose: poriferasterol glucosyltransferase in the process of differentiation of a true slime mold, Physarum polycephalum." Biochim Biophys Acta 992(3);412-5. PMID: 2528379

Sharma07: Sharma LK, Madina BR, Chaturvedi P, Sangwan RS, Tuli R (2007). "Molecular cloning and characterization of one member of 3beta-hydroxy sterol glucosyltransferase gene family in Withania somnifera." Arch Biochem Biophys 460(1);48-55. PMID: 17324374


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sat Dec 20, 2014, BIOCYC13B.