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MetaCyc Reaction: 2.4.1.19

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.4.1.19

Enzymes and Genes:

Archaeoglobus fulgidus 7324 : cyclodextrin glucanotransferase Inferred from experiment : cgt
Thermococcus sp. B1001 : cyclomaltodextrin glucanotransferase Inferred from experiment : cgtA

In Pathway: starch degradation IV , starch degradation III

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

Reaction Locations: extracellular space

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Marked as unbalanced.

Enzyme Commission Primary Name: cyclomaltodextrin glucanotransferase

Enzyme Commission Synonyms: Bacillus macerans amylase, cyclodextrin glucanotransferase, α-cyclodextrin glucanotransferase, α-cyclodextrin glycosyltransferase, β-cyclodextrin glucanotransferase, β-cyclodextrin glycosyltransferase, γ-cyclodextrin glycosyltransferase, cyclodextrin glycosyltransferase, cyclomaltodextrin glucotransferase, cyclomaltodextrin glycosyltransferase, konchizaimu, α-1,4-glucan 4-glycosyltransferase, cyclizing, BMA, CGTase, neutral-cyclodextrin glycosyltransferase, 1,4-α-D-glucan 4-α-D-(1,4-α-D-glucano)-transferase (cyclizing)

Enzyme Commission Summary:
The enzyme cyclizes a part of a (1→4)-α-D-glucan chain by formation of a (1→4)-α-D-glucosidic bond.

Cyclodextrins (Schardinger dextrins) of various sizes (6,7,8, etc. glucose units) are formed reversibly from starch and similar substrates.

Will also disproportionate linear maltodextrins without cyclizing (cf. EC 2.4.1.25, 4-α-glucanotransferase).

Citations: [Labes07, DePinto68, Schwimmer53]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:2.4.1.19 , ENZYME:EC:2.4.1.19 , IUBMB-ExplorEnz:EC:2.4.1.19

Credits:
Created 22-Feb-2011 by Fulcher CA , SRI International


References

DePinto68: DePinto JA, Campbell LL (1968). "Purification and properties of the amylase of Bacillus macerans." Biochemistry 7(1);114-20. PMID: 5758537

Labes07: Labes A, Schonheit P (2007). "Unusual starch degradation pathway via cyclodextrins in the hyperthermophilic sulfate-reducing archaeon Archaeoglobus fulgidus strain 7324." J Bacteriol 189(24);8901-13. PMID: 17921308

Schwimmer53: Schwimmer S (1953). "Evidence for the purity of Schardinger dextrinogenase." Arch Biochem Biophys 43(1);108-17. PMID: 13031665


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Tue Jul 7, 2015, BIOCYC14B.