Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 2.7.9.4

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.7.9.4

Enzymes and Genes:
glucan, water dikinase Inferred from experiment : GWD ( Arabidopsis thaliana col )

In Pathway: starch degradation II

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

Reaction Locations: chloroplast stroma

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Marked as unbalanced.

Enzyme Commission Primary Name: α-glucan, water dikinase

Enzyme Commission Synonyms: starch-related R1 protein, GWD

Enzyme Commission Summary:
ATP appears to be the only phosphate donor.

No activity could be detected using GTP, UTP, phosphoenolpyruvate or diphosphate.

The protein phosphorylates glucans at both the C-6 and C-3 position of the glucosyl residues.

The protein phosphorylates itself with the β-phosphate of ATP, which is then transferred to the glucan.

Citations: [Fettke09, Hejazi08, Ritte06, Ritte02]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:2.7.9.4 , ENZYME:EC:2.7.9.4 , IUBMB-ExplorEnz:EC:2.7.9.4

Credits:
Created 28-Feb-2011 by Dreher KA , TAIR


References

Fettke09: Fettke J, Hejazi M, Smirnova J, Hochel E, Stage M, Steup M (2009). "Eukaryotic starch degradation: integration of plastidial and cytosolic pathways." J Exp Bot 60(10);2907-22. PMID: 19325165

Hejazi08: Hejazi M, Fettke J, Haebel S, Edner C, Paris O, Frohberg C, Steup M, Ritte G (2008). "Glucan, water dikinase phosphorylates crystalline maltodextrins and thereby initiates solubilization." Plant J 55(2);323-34. PMID: 18419779

Ritte02: Ritte G, Lloyd JR, Eckermann N, Rottmann A, Kossmann J, Steup M (2002). "The starch-related R1 protein is an alpha -glucan, water dikinase." Proc Natl Acad Sci U S A 99(10);7166-71. PMID: 12011472

Ritte06: Ritte G, Heydenreich M, Mahlow S, Haebel S, Kotting O, Steup M (2006). "Phosphorylation of C6- and C3-positions of glucosyl residues in starch is catalysed by distinct dikinases." FEBS Lett 580(20);4872-6. PMID: 16914145


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Mon Nov 24, 2014, BIOCYC14B.