|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 188.8.131.52
Enzymes and Genes:
|Corynebacterium glutamicum ATCC 13032:||Zn2+-dependent alcohol dehydrogenase: adhA|
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: alcohol dehydrogenase
Enzyme Commission Synonyms: aldehyde reductase, ADH, alcohol dehydrogenase (NAD), aliphatic alcohol dehydrogenase, ethanol dehydrogenase, NAD-dependent alcohol dehydrogenase, NAD-specific aromatic alcohol dehydrogenase, NADH-alcohol dehydrogenase, NADH-aldehyde dehydrogenase, primary alcohol dehydrogenase, yeast alcohol dehydrogenase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): 21.624023 [Latendresse13]
Enzyme Commission Summary:
A zinc protein. Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol. The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.
Instance reactions of [a primary alcohol + NAD+ ↔ an aldehyde + NADH + H+] (184.108.40.206):
i1: butanal + NADH + H+ → n-butanol + NAD+ (1.1.1.-)
i2: n-propanol + NAD+ ↔ propanal + NADH + H+ (220.127.116.11)
i3: ethanol + NAD+ ↔ acetaldehyde + NADH + H+ (18.104.22.168)
i4: phytol + NAD+ → phytenal + NADH + H+ (22.214.171.124)
i5: 1-octanol + NAD+ = octanal + NADH + H+ (126.96.36.199)
i6: 1-hexanol + NAD+ ← hexanal + NADH + H+ (1.1.1.-)
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