Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 2.1.1.223

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Macromolecule Reactions Polynucleotide-Reactions RNA-Reactions tRNA-Reactions

EC Number: 2.1.1.223

Enzymes and Genes:
tRNA m6A37 methyltransferase Inferred from experiment : yfiC ( Escherichia coli K-12 substr. MG1655 )

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: tRNA1Val (adenine37-N6)-methyltransferase

Enzyme Commission Synonyms: YfiC

Standard Gibbs Free Energy (ΔrG in kcal/mol): -34.74228 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
The enzyme specifically methylates adenine37 in tRNA1Val (anticodon cmo5UAC).

Citations: [Golovina09]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:2.1.1.223 , ENZYME:EC:2.1.1.223 , IUBMB-ExplorEnz:EC:2.1.1.223

Credits:
Created 21-Jun-2011 by Kothari A , SRI International


References

Golovina09: Golovina AY, Sergiev PV, Golovin AV, Serebryakova MV, Demina I, Govorun VM, Dontsova OA (2009). "The yfiC gene of E. coli encodes an adenine-N6 methyltransferase that specifically modifies A37 of tRNA1Val(cmo5UAC)." RNA 15(6);1134-41. PMID: 19383770

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sat Nov 22, 2014, BIOCYC13A.