|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Macromolecule Reactions → Polynucleotide-Reactions → RNA-Reactions → tRNA-Reactions|
EC Number: 188.8.131.52
Enzymes and Genes:
|Escherichia coli K-12 substr. MG1655 :||tRNA m6A37 methyltransferase
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: tRNA1Val (adenine37-N6)-methyltransferase
Enzyme Commission Synonyms: YfiC
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -34.74228 [Latendresse13]
Enzyme Commission Summary:
The enzyme specifically methylates adenine37 in tRNA1Val (anticodon cmo5UAC).
Golovina09: Golovina AY, Sergiev PV, Golovin AV, Serebryakova MV, Demina I, Govorun VM, Dontsova OA (2009). "The yfiC gene of E. coli encodes an adenine-N6 methyltransferase that specifically modifies A37 of tRNA1Val(cmo5UAC)." RNA 15(6);1134-41. PMID: 19383770
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