MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateMacromolecule ReactionsPolynucleotide-ReactionsRNA-ReactionstRNA-Reactions

EC Number:

Enzymes and Genes:

Escherichia coli K-12 substr. MG1655: tRNA m6A37 methyltransferaseInferred from experiment: yfiC

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: tRNA1Val (adenine37-N6)-methyltransferase

Enzyme Commission Synonyms: YfiC

Taxonomic Range: Bacteria

Standard Gibbs Free Energy (ΔrG in kcal/mol): -34.74228Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
The enzyme specifically methylates adenine37 in tRNA1Val (anticodon cmo5UAC).

Citations: [Golovina09]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:

Created 21-Jun-2011 by Kothari A, SRI International


Golovina09: Golovina AY, Sergiev PV, Golovin AV, Serebryakova MV, Demina I, Govorun VM, Dontsova OA (2009). "The yfiC gene of E. coli encodes an adenine-N6 methyltransferase that specifically modifies A37 of tRNA1Val(cmo5UAC)." RNA 15(6);1134-41. PMID: 19383770

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Tue Dec 1, 2015, biocyc11.