Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 3.5.1.110

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions Composite Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.5.1.110

Enzymes and Genes:
peroxyureidoacrylate / ureidoacrylate amido hydrolase : rutB ( Escherichia coli K-12 substr. MG1655 )

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: peroxyureidoacrylate/ureidoacrylate amidohydrolase

Enzyme Commission Synonyms: RutB

Sub-reactions:
(Z)-3-ureidoacrylate peracid + H2O → carbamate + (Z)-3-peroxyaminoacrylate + H+ ,
carbamate + 2 H+ → ammonium + CO2

Standard Gibbs Free Energy (ΔrG in kcal/mol): 1.4970016 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
The enzyme also shows activity towards ureidoacrylate. Part of the Rut pyrimidine catabolic pathway.

Citations: [Kim10e]

Relationship Links: BRENDA:EC:3.5.1.110 , ENZYME:EC:3.5.1.110 , IUBMB-ExplorEnz:EC:3.5.1.110

Credits:
Created 06-Dec-2011 by Caspi R , SRI International


References

Kim10e: Kim KS, Pelton JG, Inwood WB, Andersen U, Kustu S, Wemmer DE (2010). "The Rut pathway for pyrimidine degradation: novel chemistry and toxicity problems." J Bacteriol 192(16):4089-102. PMID: 20400551

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Thu Dec 18, 2014, BIOCYC14A.