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MetaCyc Reaction: 2.1.1.21

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.1.1.21

Enzymes and Genes:

Aminobacter aminovorans : N-methyl-L-glutamate synthase Inferred from experiment
Methyloversatilis universalis : N-methyl-L-glutamate synthase Inferred from experiment : mgsB , mgsA , mgsC

In Pathway: methylamine degradation II

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: methylamine—glutamate N-methyltransferase

Enzyme Commission Synonyms: N-methylglutamate synthase, methylamine-glutamate methyltransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -1.5971222 Inferred by computational analysis [Latendresse13]

Citations: [Chen10, Shaw66]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:2.1.1.21 , ENZYME:EC:2.1.1.21 , IUBMB-ExplorEnz:EC:2.1.1.21

Credits:
Created 08-Dec-2011 by Caspi R , SRI International


References

Chen10: Chen Y, Scanlan J, Song L, Crombie A, Rahman MT, Schafer H, Murrell JC (2010). "{gamma}-Glutamylmethylamide is an essential intermediate in the metabolism of methylamine by Methylocella silvestris." Appl Environ Microbiol 76(13);4530-7. PMID: 20472738

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Shaw66: Shaw WV, Tsai L, Stadtman ER (1966). "The enzymatic synthesis of N-methylglutamic acid." J Biol Chem 241(4);935-45. PMID: 5905132


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sat May 23, 2015, BIOCYC13B.