Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 2.1.1.21

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.1.1.21

Enzymes and Genes:
N-methyl-L-glutamate synthase Inferred from experiment : mgsB , mgsA , mgsC ( Methyloversatilis universalis )
N-methyl-L-glutamate synthase Inferred from experiment ( Aminobacter aminovorans )

In Pathway: methylamine degradation II

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: methylamine—glutamate N-methyltransferase

Enzyme Commission Synonyms: N-methylglutamate synthase, methylamine-glutamate methyltransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -1.5971222 Inferred by computational analysis [Latendresse13]

Citations: [Chen10c, Shaw66]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:2.1.1.21 , ENZYME:EC:2.1.1.21 , IUBMB-ExplorEnz:EC:2.1.1.21

Credits:
Created 08-Dec-2011 by Caspi R , SRI International


References

Chen10c: Chen Y, Scanlan J, Song L, Crombie A, Rahman MT, Schafer H, Murrell JC (2010). "{gamma}-Glutamylmethylamide is an essential intermediate in the metabolism of methylamine by Methylocella silvestris." Appl Environ Microbiol 76(13);4530-7. PMID: 20472738

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Shaw66: Shaw WV, Tsai L, Stadtman ER (1966). "The enzymatic synthesis of N-methylglutamic acid." J Biol Chem 241(4);935-45. PMID: 5905132


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sun Nov 23, 2014, biocyc14.