Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 1.14.13.-

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 1.14.13.-

Sub-reaction of:
1.14.13.151: linalool + 2 NADH + 2 H+ + 2 oxygen → (6E)-8-oxolinalool + 2 NAD+ + 3 H2O

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 1.14.13 -- With NADH or NADPH as one donor, and incorporation of one atom of oxygen

Standard Gibbs Free Energy (ΔrG in kcal/mol): -102.42581 Inferred by computational analysis [Latendresse13]

Summary:
A heme-thiolate protein (P-450). The secondary electron donor is a specific [2Fe-2S] ferredoxin from the same bacterial strain.

Citations: [Bhattacharyya84, Ullah90, Ropp93]

Unification Links: Rhea:32639

Credits:
Created 23-Jan-2012 by Caspi R , SRI International


References

Bhattacharyya84: Bhattacharyya, P.K., Samanta, T.B., Ullah, A.H.J., Gunsalus, I.C. (1984). "Chemical probes into the active centre of a heme thiolate monoxygenase." Proc. Indian Acad. Sci., Chem. Sci. 93: 1289-1304.

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Ropp93: Ropp JD, Gunsalus IC, Sligar SG (1993). "Cloning and expression of a member of a new cytochrome P-450 family: cytochrome P-450lin (CYP111) from Pseudomonas incognita." J Bacteriol 175(18);6028-37. PMID: 8376348

Ullah90: Ullah AJ, Murray RI, Bhattacharyya PK, Wagner GC, Gunsalus IC (1990). "Protein components of a cytochrome P-450 linalool 8-methyl hydroxylase." J Biol Chem 265(3);1345-51. PMID: 2295633


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Tue Nov 25, 2014, BIOCYC14B.