MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical ReactionsProtein-Modification Reactions
Reactions Classified By SubstrateMacromolecule ReactionsProtein-ReactionsProtein-Modification Reactions

EC Number:

Enzymes and Genes:

Listeria monocytogenes: lipoyl amidotransferase: lipL

In Pathway: lipoate salvage II

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: lipoyl amidotransferase

Enzyme Commission Synonyms: LipL (gene name, ambiguous)

Standard Gibbs Free Energy (ΔrG in kcal/mol): 0.0Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
In the bacterium Listeria monocytogenes the enzyme takes part in a pathway for scavenging of lipoic acid. The enzyme is bound to 2-oxo-acid dehydrogenases such as the pyruvate dehydrogenase complex, where it transfers the lipoyl moiety from lipoyl-[glycine cleavage system H] to the E2 subunits of the complexes.

Citations: [Christensen11a]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:

Created 31-Jan-2012 by Caspi R, SRI International


Christensen11a: Christensen QH, Hagar JA, O'Riordan MX, Cronan JE (2011). "A complex lipoate utilization pathway in Listeria monocytogenes." J Biol Chem 286(36);31447-56. PMID: 21768091

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Wed Nov 25, 2015, biocyc13.