|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
Enzymes and Genes:
|Thiobacillus thioparus THI 115:||thiocyanate hydrolase: scnA, scnB, scnC|
In Pathway: thiocyanate degradation II
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: thiocyanate hydrolase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): 37.684002 [Latendresse13]
Enzyme Commission Summary:
This reaction is different from the one described by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB). The reaction is different in that the official EC reaction represents the ionic form of thiocyanate (NCS -), and thus requires an hydroxy group on the products side in order to balance it.
Katayama92: Katayama Y, Narahara Y, Inoue Y, Amano F, Kanagawa T, Kuraishi H (1992). "A thiocyanate hydrolase of Thiobacillus thioparus. A novel enzyme catalyzing the formation of carbonyl sulfide from thiocyanate." J Biol Chem 1992;267(13);9170-5. PMID: 1577754
Katayama98: Katayama Y, Matsushita Y, Kaneko M, Kondo M, Mizuno T, Nyunoya H (1998). "Cloning of genes coding for the three subunits of thiocyanate hydrolase of Thiobacillus thioparus THI 115 and their evolutionary relationships to nitrile hydratase." J Bacteriol 1998;180(10);2583-9. PMID: 9573140
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