|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 220.127.116.11
In Pathway: willardiine and isowillardiine biosynthesis
Supersedes EC number: 18.104.22.168
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: uracilylalanine synthase
Enzyme Commission Synonyms: O3-acetyl-L-serine acetate-lyase (adding uracil), isowillardiine synthase, willardiine synthase, 3-O-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase, O3-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -3.5541077 [Latendresse13]
Enzyme Commission Summary:
The enzyme produces the non-proteinogenic amino acid L-willardiine, which is naturally found in the plants Mariosousa willardiana, Mimosa pigra, and Pisum sativum (pea). The enzyme from Pisum species also produces L-isowillardiine. Not identical with EC 22.214.171.124, cysteine synthase.
Ahmmad84: Ahmmad, Mohammad A.S., Maskall, C. Sidney, Brown, Eric G. (1984). "Partial purification and properties of willardiine and isowillardiine synthase activity from Pisum sativum." Phytochemistry, 1984, 23(2):265-270.
Murakoshi78: Murakoshi, Isamu, Ikegami, Fumio, Ookawa, Noriyuki, Ariki, Takuichi, Haginiwa, Joju, Kuo, Yu-Haey (1978). "Biosynthesis of the uracilylalanines willardiine and isowillardiine in higher plants." Phytochemistry, 1978, 17:1571-1576.
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