|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
Enzymes and Genes:
purine nucleotidase : yrfG ( Escherichia coli K-12 substr. MG1655 )
alkaline phosphatase : phoA ( Escherichia coli K-12 substr. MG1655 )
cytosolic 5'-nucleotidase II : NT5C2 ( Homo sapiens )
5'-nucleotidase ( Solanum tuberosum )
5'-nucleotidase : NT5E ( Homo sapiens )
UMP phosphatase : umpH ( Escherichia coli K-12 substr. MG1655 )
acid phosphatase / phosphotransferase : aphA ( Escherichia coli K-12 substr. MG1655 )
In Pathway: adenosine nucleotides degradation I
Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .
Reaction Locations: cytosol, periplasmic space (sensu Gram-negative Bacteria)
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: 5′-nucleotidase
Enzyme Commission Synonyms: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): 7.2170105 [Latendresse13]
Enzyme Commission Summary:
Wide specificity for 5-nucleotides.
Instance reaction of [a ribonucleoside 5'-monophosphate + H2O → a ribonucleoside + phosphate] (22.214.171.124):
i1: IMP + H2O → inosine + phosphate (126.96.36.199)
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