|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 220.127.116.11
Enzymes and Genes:
|Escherichia coli K-12 substr. MG1655:||purine nucleotidase: yrfG|
UMP phosphatase: umpH
broad specificity 5'(3')-nucleotidase and polyphosphatase: umpG
acid phosphatase / phosphotransferase: aphA
|Homo sapiens:||cytosolic 5'-nucleotidase II: NT5C2|
Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.
Mass balance status: Balanced.
Enzyme Commission Primary Name: 5′-nucleotidase
Enzyme Commission Synonyms: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): 7.2170105 [Latendresse13]
Enzyme Commission Summary:
Wide specificity for 5-nucleotides.
Instance reaction of [a ribonucleoside 5'-monophosphate + H2O → a ribonucleoside + phosphate] (18.104.22.168):
i1: GMP + H2O → guanosine + phosphate (22.214.171.124)
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