Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 2.4.1.271

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.4.1.271

Enzymes and Genes:
crocetin glucosyltransferase Inferred from experiment : UGT75L6 ( Gardenia jasminoides )
crocetin glucosyltransferase Inferred from experiment : GLT2 ( Crocus sativus )
UDP-glucose:crocetin 8,8'-glucosyltransferase Inferred from experiment ( Crocus sativus )

In Pathway: crocetin esters biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: crocetin glucosyltransferase

Enzyme Commission Synonyms: crocetin GTase, UGTCs2

Standard Gibbs Free Energy (ΔrG in kcal/mol): 7.1758423 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
In the plants Crocus sativus and Gardenia jasminoides this enzyme esterifies a free carboxyl group of crocetin and some crocetin glycosyl esters. The enzyme from Gardenia jasminoides can also form glucosyl esters with 4-coumarate, caffeate and ferulate [Nagatoshi12].

Citations: [Moraga04, Cote00]

Gene-Reaction Schematic: ?

Unification Links: Rhea:31466

Relationship Links: BRENDA:EC:2.4.1.271 , ENZYME:EC:2.4.1.271 , IUBMB-ExplorEnz:EC:2.4.1.271

Credits:
Revised 10-Apr-2011 by Caspi R , SRI International


References

Cote00: Cote F., Cormier F., Dufresne C., Willemot C. (2000). "Properties of a glucosyltransferase involved in crocin synthesis." Plant Science 153:55-63.

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Moraga04: Moraga AR, Nohales PF, Perez JA, Gomez-Gomez L (2004). "Glucosylation of the saffron apocarotenoid crocetin by a glucosyltransferase isolated from Crocus sativus stigmas." Planta 219(6);955-66. PMID: 15605174

Nagatoshi12: Nagatoshi M, Terasaka K, Owaki M, Sota M, Inukai T, Nagatsu A, Mizukami H (2012). "UGT75L6 and UGT94E5 mediate sequential glucosylation of crocetin to crocin in Gardenia jasminoides." FEBS Lett 586(7);1055-61. PMID: 22569263


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Thu Dec 18, 2014, BIOCYC13A.