|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.1681
Enzymes and Genes:
crocetin glucosyltransferase : UGT75L6 ( Gardenia jasminoides )
crocetin glucosyltransferase : GLT2 ( Crocus sativus )
UDP-glucose:crocetin 8,8'-glucosyltransferase ( Crocus sativus )
In Pathway: crocetin esters biosynthesis
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: crocetin glucosyltransferase
Enzyme Commission Synonyms: crocetin GTase, UGTCs2
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): 7.1758423 [Latendresse13]
Enzyme Commission Summary:
In the plants Crocus sativus and Gardenia jasminoides this enzyme esterifies a free carboxyl group of crocetin and some crocetin glycosyl esters. The enzyme from Gardenia jasminoides can also form glucosyl esters with 4-coumarate, caffeate and ferulate [Nagatoshi12].
Unification Links: Rhea:31466
Moraga04: Moraga AR, Nohales PF, Perez JA, Gomez-Gomez L (2004). "Glucosylation of the saffron apocarotenoid crocetin by a glucosyltransferase isolated from Crocus sativus stigmas." Planta 219(6);955-66. PMID: 15605174
Nagatoshi12: Nagatoshi M, Terasaka K, Owaki M, Sota M, Inukai T, Nagatsu A, Mizukami H (2012). "UGT75L6 and UGT94E5 mediate sequential glucosylation of crocetin to crocin in Gardenia jasminoides." FEBS Lett 586(7);1055-61. PMID: 22569263
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