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MetaCyc Reaction: 2.4.1.271

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.4.1.271

Enzymes and Genes:

Crocus sativus : UDP-glucose:crocetin 8,8'-glucosyltransferase Inferred from experiment
crocetin glucosyltransferase Inferred from experiment : GLT2
Gardenia jasminoides : crocetin glucosyltransferase Inferred from experiment : UGT75L6

In Pathway: crocetin esters biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: crocetin glucosyltransferase

Enzyme Commission Synonyms: crocetin GTase, UGTCs2

Standard Gibbs Free Energy (ΔrG in kcal/mol): 6.5516663 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
In the plants Crocus sativus and Gardenia jasminoides this enzyme esterifies a free carboxyl group of crocetin and some crocetin glycosyl esters. The enzyme from Gardenia jasminoides can also form glucosyl esters with 4-coumarate, caffeate and ferulate [Nagatoshi12].

Citations: [Moraga04, Cote00]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: Rhea:31470

Relationship Links: BRENDA:EC:2.4.1.271 , ENZYME:EC:2.4.1.271 , IUBMB-ExplorEnz:EC:2.4.1.271

Credits:
Revised 25-Aug-2011 by Caspi R , SRI International


References

Cote00: Cote F., Cormier F., Dufresne C., Willemot C. (2000). "Properties of a glucosyltransferase involved in crocin synthesis." Plant Science 153:55-63.

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Moraga04: Moraga AR, Nohales PF, Perez JA, Gomez-Gomez L (2004). "Glucosylation of the saffron apocarotenoid crocetin by a glucosyltransferase isolated from Crocus sativus stigmas." Planta 219(6);955-66. PMID: 15605174

Nagatoshi12: Nagatoshi M, Terasaka K, Owaki M, Sota M, Inukai T, Nagatsu A, Mizukami H (2012). "UGT75L6 and UGT94E5 mediate sequential glucosylation of crocetin to crocin in Gardenia jasminoides." FEBS Lett 586(7);1055-61. PMID: 22569263


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sun Aug 30, 2015, biocyc14.