|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 188.8.131.521
Enzymes and Genes:
|Crocus sativus:||UDP-glucose:crocetin 8,8'-glucosyltransferase|
crocetin glucosyltransferase: GLT2
|Gardenia jasminoides:||crocetin glucosyltransferase: UGT75L6|
In Pathway: crocetin esters biosynthesis
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: crocetin glucosyltransferase
Enzyme Commission Synonyms: crocetin GTase, UGTCs2
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): 6.5516663 [Latendresse13]
Enzyme Commission Summary:
In the plants Crocus sativus and Gardenia jasminoides this enzyme esterifies a free carboxyl group of crocetin and some crocetin glycosyl esters. The enzyme from Gardenia jasminoides can also form glucosyl esters with 4-coumarate, caffeate and ferulate [Nagatoshi12].
Moraga04: Moraga AR, Nohales PF, Perez JA, Gomez-Gomez L (2004). "Glucosylation of the saffron apocarotenoid crocetin by a glucosyltransferase isolated from Crocus sativus stigmas." Planta 219(6);955-66. PMID: 15605174
Nagatoshi12: Nagatoshi M, Terasaka K, Owaki M, Sota M, Inukai T, Nagatsu A, Mizukami H (2012). "UGT75L6 and UGT94E5 mediate sequential glucosylation of crocetin to crocin in Gardenia jasminoides." FEBS Lett 586(7);1055-61. PMID: 22569263
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