twitter

MetaCyc Reaction: 3.1.7.11

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.1.7.11

Enzymes and Genes:

Cinnamomum tenuipile : geraniol synthase Inferred from experiment : GES
Ocimum basilicum : geraniol synthase Inferred from experiment : GES
Perilla citriodora : C-geraniol synthase Inferred from experiment : PcTps-C
Perilla frutescens : P-geraniol synthase Inferred from experiment : PfTps-PL
Zea mays : geraniol synthase Inferred from experiment : TPS1

In Pathway: geraniol and geranial biosynthesis , secologanin and strictosidine biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: geranyl diphosphate diphosphatase

Enzyme Commission Synonyms: geraniol synthase, geranyl pyrophosphate pyrophosphatase, GES, CtGES

Standard Gibbs Free Energy (ΔrG in kcal/mol): -3.742981 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Isolated from Ocimum basilicum (basil) and Cinnamomum tenuipile (camphor tree). Requires Mg2+ or Mn2+. The mechanism involves a geranyl cation [Iijima04a]. Neryl diphosphate is hydrolysed more slowly. May be the same as EC 3.1.7.3 monoterpenyl-diphosphatase.

Citations: [Yang05a]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R08396 , Rhea:32682

Relationship Links: BRENDA:EC:3.1.7.11 , ENZYME:EC:3.1.7.11 , IUBMB-ExplorEnz:EC:3.1.7.11

Credits:
Revised 23-Jan-2012 by Caspi R , SRI International


References

Iijima04a: Iijima Y, Gang DR, Fridman E, Lewinsohn E, Pichersky E (2004). "Characterization of geraniol synthase from the peltate glands of sweet basil." Plant Physiol 134(1);370-9. PMID: 14657409

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Yang05a: Yang T, Li J, Wang HX, Zeng Y (2005). "A geraniol-synthase gene from Cinnamomum tenuipilum." Phytochemistry 66(3);285-93. PMID: 15680985


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sun Aug 2, 2015, BIOCYC14A.