Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
twitter

MetaCyc Reaction: [no EC number assigned]

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical ReactionsProtein-Modification Reactions
Reactions Classified By SubstrateMacromolecule ReactionsProtein-ReactionsProtein-Modification Reactions

Enzymes and Genes:

Bacillus subtilis subtilis 168: lipoate-protein ligaseInferred from experiment: lplJ
Escherichia coli K-12 substr. MG1655: lipoate-protein ligase AInferred from experiment: lplA
Thermoplasma acidophilum: lipoate-protein ligase AInferred from experiment: lplA, lplB

Sub-reaction of:
6.3.1.h: a [lipoyl-carrier protein]-L-lysine + ATP + (R)-lipoate = a [lipoyl-carrier protein]-N6-lipoyl-L-lysine + AMP + diphosphate + H+

In Pathway: lipoate salvage I

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Instance reaction:
lipoyl-adenylate + [glycine cleavage system lipoyl-carrier protein]-L-lysine → a [glycine-cleavage complex H protein] N6-lipoyl-L-lysine + AMP + 2 H+ (no EC#)

Standard Gibbs Free Energy (ΔrG in kcal/mol): -85.63157Inferred by computational analysis [Latendresse13]

Gene-Reaction Schematic

Gene-Reaction Schematic

Instance reaction of [lipoyl-adenylate + a [lipoyl-carrier protein]-L-lysine → a [lipoyl-carrier protein]-N6-lipoyl-L-lysine + AMP + 2 H+] (no EC#):
i1: lipoyl-adenylate + [glycine cleavage system lipoyl-carrier protein]-L-lysine → a [glycine-cleavage complex H protein] N6-lipoyl-L-lysine + AMP + 2 H+ (no EC#)

Unification Links: KEGG:R07771


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Thu Feb 11, 2016, biocyc12.