MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:

Acinetobacter sp. ADP1: wax ester synthase/acyl-CoA diacylglycerol acyltransferase bifunctional enzymeInferred from experiment: atfA
Petunia x hybrida: wax synthase/diacyglycerol acyltransferase [multifunctional]Inferred from experiment: WS1

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: long-chain-alcohol O-fatty-acyltransferase

Enzyme Commission Synonyms: wax synthase, wax-ester synthase

Taxonomic Range: Metazoa, Bacteria , Viridiplantae

Standard Gibbs Free Energy (ΔrG in kcal/mol): -3.610077Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Transfers saturated or unsaturated acyl residues of chain-length C18 to C20 to long-chain alcohols, forming waxes. The best acceptor is cis-icos-11-en-1-ol.

Citations: [King07a, Wu81]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:

Revised 04-Apr-2012 by Caspi R, SRI International


King07a: King A, Nam JW, Han J, Hilliard J, Jaworski JG (2007). "Cuticular wax biosynthesis in petunia petals: cloning and characterization of an alcohol-acyltransferase that synthesizes wax-esters." Planta 226(2);381-94. PMID: 17323080

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Wu81: Wu XY, Moreau RA, Stumpf PK (1981). "Studies of biosynthesis of waxes by developing jojoba seed: III. Biosynthesis of wax esters from Acyl-CoA and long chain alcohols." Lipids 16(12);897-902.

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.5 on Sat Nov 28, 2015, BIOCYC13A.