Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 2.3.1.75

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.3.1.75

Enzymes and Genes:
wax ester synthase/acyl-CoA diacylglycerol acyltransferase bifunctional enzyme Inferred from experiment : atfA ( Acinetobacter sp. ADP1 )
wax synthase/diacyglycerol acyltransferase [multifunctional] Inferred from experiment : WS1 ( Petunia x hybrida )

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: long-chain-alcohol O-fatty-acyltransferase

Enzyme Commission Synonyms: wax synthase, wax-ester synthase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -3.610077 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Transfers saturated or unsaturated acyl residues of chain-length C18 to C20 to long-chain alcohols, forming waxes. The best acceptor is cis-icos-11-en-1-ol.

Citations: [King07, Wu81]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:2.3.1.75 , ENZYME:EC:2.3.1.75 , IUBMB-ExplorEnz:EC:2.3.1.75

Credits:
Revised 04-Apr-2012 by Caspi R , SRI International


References

King07: King A, Nam JW, Han J, Hilliard J, Jaworski JG (2007). "Cuticular wax biosynthesis in petunia petals: cloning and characterization of an alcohol-acyltransferase that synthesizes wax-esters." Planta 226(2);381-94. PMID: 17323080

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Wu81: Wu XY, Moreau RA, Stumpf PK (1981). "Studies of biosynthesis of waxes by developing jojoba seed: III. Biosynthesis of wax esters from Acyl-CoA and long chain alcohols." Lipids 16(12);897-902.


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sat Nov 22, 2014, biocyc14.