Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 3.1.1.94

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.1.1.94

Enzymes and Genes:
versiconal hemiacetal acetate esterase Inferred from experiment : estA ( Aspergillus parasiticus )

In Pathway: versicolorin B biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: versiconal hemiacetal acetate esterase

Enzyme Commission Synonyms: VHA esterase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -4.2871094 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Isolated from the mold Aspergillus parasiticus. Involved in a metabolic grid that leads to aflatoxin biosynthesis.

Citations: [Kusumoto96, Chang04b]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:3.1.1.94 , ENZYME:EC:3.1.1.94 , IUBMB-ExplorEnz:EC:3.1.1.94


References

Chang04b: Chang PK, Yabe K, Yu J (2004). "The Aspergillus parasiticus estA-encoded esterase converts versiconal hemiacetal acetate to versiconal and versiconol acetate to versiconol in aflatoxin biosynthesis." Appl Environ Microbiol 70(6);3593-9. PMID: 15184162

Kusumoto96: Kusumoto K, Hsieh DP (1996). "Purification and characterization of the esterases involved in aflatoxin biosynthesis in Aspergillus parasiticus." Can J Microbiol 42(8);804-10. PMID: 8776851

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Wed Nov 26, 2014, biocyc14.