MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:

Aspergillus parasiticus: versiconal hemiacetal acetate esteraseInferred from experiment: estA

In Pathway: versicolorin B biosynthesis

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: versiconal hemiacetal acetate esterase

Enzyme Commission Synonyms: VHA esterase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -4.2871094Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Isolated from the mold Aspergillus parasiticus. Involved in a metabolic grid that leads to aflatoxin biosynthesis.

Citations: [Kusumoto96, Chang04]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


Chang04: Chang PK, Yabe K, Yu J (2004). "The Aspergillus parasiticus estA-encoded esterase converts versiconal hemiacetal acetate to versiconal and versiconol acetate to versiconol in aflatoxin biosynthesis." Appl Environ Microbiol 70(6);3593-9. PMID: 15184162

Kusumoto96: Kusumoto K, Hsieh DP (1996). "Purification and characterization of the esterases involved in aflatoxin biosynthesis in Aspergillus parasiticus." Can J Microbiol 42(8);804-10. PMID: 8776851

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Wed May 4, 2016, biocyc13.