|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 184.108.40.206
Enzymes and Genes:
|Aspergillus parasiticus :||versiconal hemiacetal acetate esterase
In Pathway: versicolorin B biosynthesis
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: versiconal hemiacetal acetate esterase
Enzyme Commission Synonyms: VHA esterase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -4.2871094 [Latendresse13]
Enzyme Commission Summary:
Isolated from the mold Aspergillus parasiticus. Involved in a metabolic grid that leads to aflatoxin biosynthesis.
Chang et al., 2004: Chang PK, Yabe K, Yu J (2004). "The Aspergillus parasiticus estA-encoded esterase converts versiconal hemiacetal acetate to versiconal and versiconol acetate to versiconol in aflatoxin biosynthesis." Appl Environ Microbiol 70(6);3593-9. PMID: 15184162
Kusumoto & Hsieh, 1996: Kusumoto K, Hsieh DP (1996). "Purification and characterization of the esterases involved in aflatoxin biosynthesis in Aspergillus parasiticus." Can J Microbiol 42(8);804-10. PMID: 8776851
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