|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 22.214.171.124
Enzymes and Genes:
|Homo sapiens:||α-methylacyl-CoA racemase: AMACR|
|Rattus norvegicus:||α-methylacyl-CoA racemase: Amacr|
In Pathway: bile acid biosynthesis, neutral pathway
Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: α-methylacyl-CoA racemase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): 0.0 [Latendresse13]
Enzyme Commission Summary:
α-methyl-branched acyl-CoA derivatives with chain lengths of more than C10 are substrates. Also active towards some aromatic compounds (e.g. ibuprofen) and bile acid intermediates, such as trihydroxycoprostanoyl-CoA. Not active towards free acids.
Unification Links: KEGG:R08739
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