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MetaCyc Reaction: 1.2.1.4

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number: 1.2.1.4

Enzymes and Genes:

Escherichia coli K-12 substr. MG1655: acetaldehyde dehydrogenaseInferred from experiment: aldB
NADPH-dependent aldehyde reductase: yqhD
Saccharomyces cerevisiae: magnesium-activated aldehyde dehydrogenase, cytosolicInferred from experiment: ALD6
potassium-activated aldehyde dehydrogenase, mitochondrial: ALD4
aldehyde dehydrogenase, mitochondrial: ALD5

In Pathway: pyruvate fermentation to acetate VIII, NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: aldehyde dehydrogenase (NADP+)

Enzyme Commission Synonyms: NADP-acetaldehyde dehydrogenase, NADP-dependent aldehyde dehydrogenase, aldehyde dehydrogenase (NADP)

Standard Gibbs Free Energy (ΔrG in kcal/mol): -16.52362Inferred by computational analysis [Latendresse13]

Citations: [Seegmiller53]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R00711, Rhea:25298

Relationship Links: BRENDA:EC:1.2.1.4, ENZYME:EC:1.2.1.4, IUBMB-ExplorEnz:EC:1.2.1.4


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Seegmiller53: Seegmiller JE (1953). "Triphosphopyridine nucleotide-linked aldehyde dehydrogenase from yeast." J Biol Chem 201(2);629-37. PMID: 13061400


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Sun Feb 7, 2016, biocyc11.