|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 220.127.116.11
Enzymes and Genes:
acetaldehyde dehydrogenase : aldB ( Escherichia coli K-12 substr. MG1655 )
magnesium-activated aldehyde dehydrogenase, cytosolic : ALD6 ( Saccharomyces cerevisiae )
aldehyde dehydrogenase, mitochondrial : ALD5 ( Saccharomyces cerevisiae )
potassium-activated aldehyde dehydrogenase, mitochondrial : ALD4 ( Saccharomyces cerevisiae )
NADPH-dependent aldehyde reductase : yqhD ( Escherichia coli K-12 substr. MG1655 )
Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: aldehyde dehydrogenase (NADP+)
Enzyme Commission Synonyms: NADP-acetaldehyde dehydrogenase, NADP-dependent aldehyde dehydrogenase, aldehyde dehydrogenase (NADP)
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -16.52362 [Latendresse13]
Instance reaction of [an aldehyde + NADP+ + H2O → a carboxylate + NADPH + 2 H+] (18.104.22.168):
i1: acetaldehyde + NADP+ + H2O → acetate + NADPH + 2 H+ (22.214.171.124)
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