Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
twitter

MetaCyc Reaction: 1.12.99.6

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number: 1.12.99.6

Enzymes and Genes:

Anabaena variabilis: uptake hydrogenaseInferred from experiment: hupL, hupS
Cupriavidus necator: [NiFe]-hydrogenase (membrane bound)Inferred from experiment: hoxZ, hoxK, hoxG
Rhodospirillum rubrum: carbon monoxide induced hydrogenaseInferred from experiment: cooH, cooU, cooX, cooL, cooK, cooM

Sub-reaction of:
1.2.99.-: carbon monoxide + H2O = CO2 + H2

In Pathway: hydrogen oxidation I (aerobic), hydrogen production VI

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: hydrogenase (acceptor)

Enzyme Commission Synonyms: H2 producing hydrogenase[ambiguous], hydrogen-lyase[ambiguous], hydrogenlyase[ambiguous], uptake hydrogenase[ambiguous], hydrogen:(acceptor) oxidoreductase

Enzyme Commission Summary:
Uses molecular hydrogen for the reduction of a variety of substances. Contains iron-sulfur clusters. The enzyme from some sources contains nickel.

Citations: [Adams80, Vignais01]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R07182, Rhea:12116

Relationship Links: BRENDA:EC:1.12.99.6, ENZYME:EC:1.12.99.6, IUBMB-ExplorEnz:EC:1.12.99.6

Credits:
Revised 09-Dec-2011 by Caspi R, SRI International


References

Adams80: Adams MW, Mortenson LE, Chen JS (1980). "Hydrogenase." Biochim Biophys Acta 594(2-3);105-76. PMID: 6786341

Vignais01: Vignais PM, Billoud B, Meyer J (2001). "Classification and phylogeny of hydrogenases." FEMS Microbiol Rev 25(4);455-501. PMID: 11524134


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Tue May 3, 2016, biocyc14.