MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:

Anabaena variabilis: uptake hydrogenaseInferred from experiment: hupL, hupS
Cupriavidus necator: [NiFe]-hydrogenase (membrane bound)Inferred from experiment: hoxZ, hoxK, hoxG
Rhodospirillum rubrum: carbon monoxide induced hydrogenaseInferred from experiment: cooH, cooU, cooX, cooL, cooK, cooM

Sub-reaction of:
1.2.99.-: carbon monoxide + H2O = CO2 + H2

In Pathway: hydrogen oxidation I (aerobic), hydrogen production VI

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: hydrogenase (acceptor)

Enzyme Commission Synonyms: H2 producing hydrogenase[ambiguous], hydrogen-lyase[ambiguous], hydrogenlyase[ambiguous], uptake hydrogenase[ambiguous], hydrogen:(acceptor) oxidoreductase

Enzyme Commission Summary:
Uses molecular hydrogen for the reduction of a variety of substances. Contains iron-sulfur clusters. The enzyme from some sources contains nickel.

Citations: [Adams80, Vignais01]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R07182, Rhea:12116

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:

Revised 09-Dec-2011 by Caspi R, SRI International


Adams80: Adams MW, Mortenson LE, Chen JS (1980). "Hydrogenase." Biochim Biophys Acta 594(2-3);105-76. PMID: 6786341

Vignais01: Vignais PM, Billoud B, Meyer J (2001). "Classification and phylogeny of hydrogenases." FEMS Microbiol Rev 25(4);455-501. PMID: 11524134

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.5 on Tue Dec 1, 2015, BIOCYC14B.