Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 1.12.99.6

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 1.12.99.6

Enzymes and Genes:
carbon monoxide induced hydrogenase Inferred from experiment : cooH , cooU , cooX , cooL , cooK , cooM ( Rhodospirillum rubrum )
uptake hydrogenase Inferred from experiment : hupL , hupS ( Anabaena variabilis )
[NiFe]-hydrogenase (membrane bound) Inferred from experiment : hoxZ , hoxK , hoxG ( Cupriavidus necator )

Sub-reaction of:
1.2.99.-: carbon monoxide + H2O = CO2 + H2

In Pathway: hydrogen oxidation I (aerobic) , hydrogen production VI

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: hydrogenase (acceptor)

Enzyme Commission Synonyms: H2 producing hydrogenase[ambiguous], hydrogen-lyase[ambiguous], hydrogenlyase[ambiguous], uptake hydrogenase[ambiguous], hydrogen:(acceptor) oxidoreductase

Enzyme Commission Summary:
Uses molecular hydrogen for the reduction of a variety of substances. Contains iron-sulfur clusters. The enzyme from some sources contains nickel.

Citations: [Adams80, Vignais01]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R07182 , Rhea:12116

Relationship Links: BRENDA:EC:1.12.99.6 , ENZYME:EC:1.12.99.6 , IUBMB-ExplorEnz:EC:1.12.99.6

Credits:
Revised 09-Dec-2011 by Caspi R , SRI International


References

Adams80: Adams MW, Mortenson LE, Chen JS (1980). "Hydrogenase." Biochim Biophys Acta 594(2-3);105-76. PMID: 6786341

Vignais01: Vignais PM, Billoud B, Meyer J (2001). "Classification and phylogeny of hydrogenases." FEMS Microbiol Rev 25(4);455-501. PMID: 11524134


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Dec 19, 2014, biocyc14.